Rugulovasine A

Base Information

Chemical Name:Rugulovasine A
CAS No.:26909-33-1
Molecular Formula:C₁₆H₁₆N₂O₂
Molecular Weight:268.315
Hs Code.:
UNII:90DEE096C5
DSSTox Substance ID:DTXSID20949700
Nikkaji Number:J237.984H
Wikidata:Q27271312
Metabolomics Workbench ID:161518
Mol file:26909-33-1.mol

Synonyms:rugulovasine A;rugulovasine A monohydrochloride, (cis-(+-))-isomer

Suppliers and Price of Rugulovasine A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Rugulovasine A

Chemical Property:

Melting Point:138° (dec)
Boiling Point:550.3°Cat760mmHg
Flash Point:286.6°C
PSA：54.12000
Density:1.32g/cm³
LogP:2.40130
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:268.121177757
Heavy Atom Count:20
Complexity:475

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2(C(CC3=CNC4=CC=CC2=C34)NC)OC1=O
Isomeric SMILES:CC1=C[C@@]2([C@H](CC3=CNC4=CC=CC2=C34)NC)OC1=O
Description A non-crystallizable alkaloid, this base has been obtained from cultures of Penicillium concavorugulosum. It is slightly laevorotatory with [α]22436 - 3.0° (c 1.0, pyridine). The five-membered lactone ring is unsaturated and on catalytic hydrogenation the alkaloid forms the crystalline dihydro derivative, m.p. l49-l5l oC. One of the nitrogen atoms is present in the indole ring, the other being a methylamino group.

Technology Process of Rugulovasine A

There total 16 articles about Rugulovasine A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: C₂₁H₂₄N₂O₄

: 26909-33-1
rugulovasine A

Guidance literature:: With 2,6-dimethylpyridine; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/ol401541t

Reference yield: 75.0%

: 74644-92-1
1,3,4,5-tetrahydro-5-hydroxy-α-methyl-4-(methylbenzamido)benzindole-5-acrylic acid γ-lactone

: 26909-33-1
rugulovasine A

Guidance literature:: With triethyloxonium fluoroborate; sodium carbonate; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/jo00193a018