6-(3-Thienyl)nicotinaldehyde

Base Information

Chemical Name:6-(3-Thienyl)nicotinaldehyde
CAS No.:834884-60-5
Molecular Formula:C₁₀H₇NOS
Molecular Weight:189.238
Hs Code.:2934999090
European Community (EC) Number:839-006-0

Synonyms:6-(3-thienyl)nicotinaldehyde;834884-60-5;6-(THIOPHEN-3-YL)NICOTINALDEHYDE;6-thiophen-3-ylpyridine-3-carbaldehyde;6-(thiophen-3-yl)pyridine-3-carbaldehyde;6-THIOPHEN-3-YL-PYRIDINE-3-CARBALDEHYDE;SCHEMBL2717858;FWJYLCWTCJHNRK-UHFFFAOYSA-N;MFCD04115422;AKOS005071601;AB19961;6-(3-Thienyl)-3-pyridinecarboxaldehyde;6-(3-thienyl)nicotinaldehyde, AldrichCPR;CS-0433389;EN300-239868;9Y-0705;F2167-2420;Z1198164392

Suppliers and Price of 6-(3-Thienyl)nicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(3-thienyl)nicotinaldehyde
25mg
$ 130.00

Matrix Scientific
6-(3-Thienyl)nicotinaldehyde >95%
5g
$ 1384.00

Matrix Scientific
6-(3-Thienyl)nicotinaldehyde >95%
1g
$ 603.00

Matrix Scientific
6-(3-Thienyl)nicotinaldehyde >95%
500mg
$ 486.00

J&W Pharmlab
6-Thiophen-3-yl-pyridine-3-carbaldehyde 96%
5g
$ 450.00

Crysdot
6-(Thiophen-3-yl)nicotinaldehyde 95+%
5g
$ 1373.00

Crysdot
6-(Thiophen-3-yl)nicotinaldehyde 95+%
1g
$ 597.00

Chemenu
6-(Thiophen-3-yl)nicotinaldehyde 95%
1g
$ 564.00

Acrotein
6-(3-Thienyl)-3-pyridinecarboxaldehyde 97%
0.25g
$ 150.34

Total 5 raw suppliers

Chemical Property of 6-(3-Thienyl)nicotinaldehyde

Chemical Property:

Melting Point:97～100℃
PSA：58.20000
LogP:2.62260
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.02483502
Heavy Atom Count:13
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

6-(3-thienyl)nicotinaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC=C1C=O)C2=CSC=C2

Technology Process of 6-(3-Thienyl)nicotinaldehyde

There total 3 articles about 6-(3-Thienyl)nicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 6165-69-1
Thien-3-ylboronic acid

: 149806-06-4
6-bromonicotinaldehyde

: 834884-60-5
6-(thiophen-3-yl)nicotinaldehyde

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; for 4h; Inert atmosphere; Reflux;
DOI:10.1021/jm400240r

Reference yield: 65.0%

: 834884-60-5
6-(thiophen-3-yl)nicotinaldehyde

Guidance literature:

Reference yield:

: 624-28-2
2,5-dibromopyridine

: 834884-60-5
6-(thiophen-3-yl)nicotinaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / 1 h / -80 °C

1.2: 1 h / -80 °C

2.1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol; water / 4 h / Inert atmosphere; Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; sodium carbonate; In diethyl ether; ethanol; hexane; water; toluene; 2.1: |Suzuki Coupling;
DOI:10.1021/jm400240r