2,3,5,6-tetrafluoro-1,1'-biphenyl

Base Information

• Chemical Name: 2,3,5,6-tetrafluoro-1,1'-biphenyl
• CAS No.: 834-89-9
• Molecular Formula: C12H6F4
• Molecular Weight: 226.173
• Mol file: 834-89-9.mol

Synonyms:2.3.5.6-Tetrafluor-biphenyl;2,3,4,5-tetrafluorobiphenyl;2,3,5,6-tetrafluoro-1,1'-biphenyl;2,3,5,6-tetrafluorobiphenyl;

Chemical Property of 2,3,5,6-tetrafluoro-1,1'-biphenyl

Chemical Property:

• PSA: 0.00000
• LogP: 3.91000

Purity/Quality:

99.0% ^*data from raw suppliers

2,3,5,6-Tetrafluorobiphenyl ≥97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,5,6-tetrafluoro-1,1'-biphenyl

There total 39 articles about 2,3,5,6-tetrafluoro-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

bromobenzene (108-86-1,52753-63-6) + 2,3,5,6-tetrafluorophenylzinc → 2,3,5,6-tetrafluorobiphenyl (834-89-9)

Guidance literature:

With nickel(II) bromide dimethoxyethane; C₇₀H₇₅BN₂; In tetrahydrofuran; N,N-dimethyl-formamide; at 50 ℃; for 12h;

Reference yield: 92.0%

1,2,4,5-Tetrafluorobenzene (327-54-8) + Phenyl triflate (17763-67-6) → 2,3,5,6-tetrafluorobiphenyl (834-89-9)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 18-crown-6 ether; 2-[bis((3,5-dimethyl-4-methoxyphenyl)phosphino)phenyl]ether; isopropylmagnesium chloride; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; at 40 ℃; for 2h; Temperature; Solvent; Reagent/catalyst;

DOI:10.1021/acscatal.7b02618

Reference yield: 92.0%

2,3,4,5,6-pentafluorobiphenyl (784-14-5) → 2,3,5,6-tetrafluorobiphenyl (834-89-9)

Guidance literature:

With H₂SiEt₂; C₁₇H₂₁BiN₂O₃; In tetrahydrofuran; at 60 ℃; for 72h; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.1c06735

upstream raw materials:

1,2,4,5-Tetrafluorobenzene

dibenzoyl peroxide

Pentafluorobenzene

2,3,5,6-Tetrafluor-4-hydrazino-biphenyl

Downstream raw materials:

(4-chlorophenyl)(2,3,5,6-tetrafluorobiphenyl-4-yl)methanol

N-(2,3,5,6-tetrafluoro-1,1'-biphenyl)-4-nitrobenzenamine

2′,2″,3′,3″,5′,5″,6′,6″-octafluoro-1,1′:4′,1″:4″,1?-quaterphenyl

2,2',3',5',6'-pentafluoro-6-nitro-4'-phenylbiphenyl