1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ACID

Base Information

• Chemical Name: 1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ACID
• CAS No.: 40469-16-7
• Molecular Formula: C₉H₁₂O₄
• Molecular Weight: 184.192
• Mol file: 40469-16-7.mol

Synonyms:4-Cyclohexene-1,2-dicarboxylicacid, 3-methyl-, (1a,2a,3a)- (9CI); cis,cis-3-Methyl-4-cyclohexene-1,2-dicarboxylicacid

Chemical Property of 1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ACID

Chemical Property:

• Vapor Pressure: 4.7E-07mmHg at 25°C
• Melting Point: 153-154 °C
• Boiling Point: 386.7°Cat760mmHg
• PKA: 4.30±0.60(Predicted)
• Flash Point: 201.8°C
• PSA: 74.60000
• Density: 1.276g/cm³
• LogP: 0.98400

Purity/Quality:

98%min ^*data from raw suppliers

3-methylcyclohex-4-ene-1,2-dicarboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ACID

There total 5 articles about 1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-methyl)tetrahydrophthalic anhydride (35438-81-4) → (+/-)-3c-methyl-cyclohex-4-ene-1r,2c-dicarboxylic acid (15941-50-1,23667-61-0,40469-16-7,40469-17-8,40469-18-9,41792-44-3)

Guidance literature:

With water;

DOI:10.1021/ja01160a070 DOI:10.1021/ja01604a035

Reference yield:

(+/-)-3c-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid-anhydride (5333-84-6,35438-81-4,35438-82-5,35438-83-6,35438-84-7,38360-97-3,51268-24-7,51268-25-8,51268-26-9,51348-45-9,55449-34-8) → (+/-)-3c-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid (15941-50-1,23667-61-0,40469-16-7,40469-17-8,40469-18-9,41792-44-3)

Guidance literature:

DOI:10.1021/ja01160a070

Reference yield:

(+/-)-3t-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid-anhydride (5333-84-6,35438-81-4,35438-82-5,35438-83-6,35438-84-7,38360-97-3,51268-24-7,51268-25-8,51268-26-9,51348-45-9,55449-34-8) → (+/-)-3t-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid (15941-50-1,23667-61-0,40469-16-7,40469-17-8,40469-18-9,41792-44-3)

Guidance literature:

DOI:10.1021/ja01160a070

upstream raw materials:

(3-methyl)tetrahydrophthalic anhydride

trans-3-methylcyclohex-4-ene-cis-1,2-dicarboxylic anhydride

(+/-)-3t-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid-anhydride

(+/-)-3c-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid-anhydride

Downstream raw materials:

(+/-)-3c-methyl-cyclohex-4-ene-1r,2t-dicarboxylic acid-anhydride

(+/-)-3t-methyl-cyclohexane-1r,2c-dicarboxylic acid

(4S,6R,9aS)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-trimethylsilanyloxy-1,6,7,9a-tetrahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester

(4R,6R,9aR)-8-Benzyloxymethyl-6-methoxy-4-methyl-5-trimethylsilanyloxy-1,6,7,9a-tetrahydro-4H-benzocycloheptene-6-carboxylic acid tert-butyl ester