4-Oxo-4-(benzhydrylamino)crotonic acid

Base Information

Chemical Name:4-Oxo-4-(benzhydrylamino)crotonic acid
CAS No.:843664-92-6
Molecular Formula:C17H15NO3
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID501220745
Nikkaji Number:J2.128.429G

Synonyms:DTXSID501220745;AKOS001263464;4-Oxo-4-(benzhydrylamino)crotonic acid;Z57704682;(2E)-4-[(Diphenylmethyl)amino]-4-oxo-2-butenoic acid;843664-92-6

Suppliers and Price of 4-Oxo-4-(benzhydrylamino)crotonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Oxo-4-(benzhydrylamino)crotonic acid

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:362

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)NC(=O)C=CC(=O)O
Isomeric SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)NC(=O)/C=C/C(=O)O

Technology Process of 4-Oxo-4-(benzhydrylamino)crotonic acid

There total 1 articles about 4-Oxo-4-(benzhydrylamino)crotonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26367-48-6
fumaric acid ethyl ester mono chloride

: 91-00-9
Benzhydrylamine

: 843664-92-6
(E)-3-(Benzhydryl-carbamoyl)-acrylic acid

Guidance literature:: fumaric acid ethyl ester mono chloride; Benzhydrylamine; With caesium carbonate; In tetrahydrofuran; at 20 ℃; for 12h;

With potassium hydroxide; In tetrahydrofuran; at 20 ℃; for 12h;
DOI:10.1016/j.tetlet.2004.11.115

Reference yield:

: 88333-03-3,10340-91-7
Benzyl isocyanide

: 1201-74-7,3082-62-0,3906-16-9,64234-21-5
1-(2-Naphthyl)ethylamine

: 843664-92-6
(E)-3-(Benzhydryl-carbamoyl)-acrylic acid

5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether: 5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether

: (1S,2S,5R,6R,7R)-7-Hydroxymethyl-3-(1-naphthalen-2-yl-ethyl)-4-oxo-10-oxa-3-aza-tricyclo[5.2.1.0^1,5]dec-8-ene-2,6-dicarboxylic acid 6-benzhydryl-amide 2-benzylamide

Guidance literature:: Benzyl isocyanide; 1-(2-Naphthyl)ethylamine; (E)-3-(Benzhydryl-carbamoyl)-acrylic acid; 5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether; In methanol; at 50 ℃; for 48h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/j.tetlet.2004.11.115

Reference yield:

: 89-93-0
ortho-methylbenzylamine

: 88333-03-3,10340-91-7
Benzyl isocyanide

: 843664-92-6
(E)-3-(Benzhydryl-carbamoyl)-acrylic acid

5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether: 5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether

: (1S,2S,5R,6R,7R)-7-Hydroxymethyl-3-(2-methyl-benzyl)-4-oxo-10-oxa-3-aza-tricyclo[5.2.1.0^1,5]dec-8-ene-2,6-dicarboxylic acid 6-benzhydryl-amide 2-benzylamide

Guidance literature:: ortho-methylbenzylamine; Benzyl isocyanide; (E)-3-(Benzhydryl-carbamoyl)-acrylic acid; 5-formylfurfuryloxymethyl-terminated poly(ethyleneglycol) monomethyl ether; In methanol; at 50 ℃; for 48h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1016/j.tetlet.2004.11.115