{[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid

Base Information

• Chemical Name: {[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid
• CAS No.: 179755-65-8
• Molecular Formula: C₂₇H₃₁N₅O₅S*2ClH
• Molecular Weight: 610.562
• DSSTox Substance ID: DTXSID80430967
• Nikkaji Number: J907.191A
• Wikidata: Q82244724,Q27451003
• Pharos Ligand ID: CRX41DZN8GG2
• ChEMBL ID: CHEMBL20240
• Mol file: 179755-65-8.mol

Synonyms:(N-(4-((1-acetimidoyl-4-piperidyl)oxy)phenyl)-N-((7-amidino-2-naphthyl)methyl)sulfamoyl)acetic acid dihydrochloride;(N-(4-((1-acetimidoyl-4-piperidyl)oxy)phenyl)-N-((7-amidino-2-naphthyl)methyl)sulfamoyl)acetic acid mesilate;YM 466;YM 60828;YM-466;YM-60828;YM466;YM60828

Chemical Property of {[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid

Chemical Property:

• PSA: 169.25000
• LogP: 5.30370
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 10
• Exact Mass: 537.20459028
• Heavy Atom Count: 38
• Complexity: 953

Purity/Quality:

99% ^*data from raw suppliers

YM60828 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=N)N1CCC(CC1)OC2=CC=C(C=C2)N(CC3=CC4=C(C=C3)C=CC(=C4)C(=N)N)S(=O)(=O)CC(=O)O
• Uses: YM 60828 is a potent, selective and orally-bioavailable Factor Xa (FXa) inhibitor; an anticogulant used in treatment of venous thromboembolic disease. A potent, selective and orally-bioavailable Factor Xa (FXa) inhibitor; an anticogulant used in treatment of venous thromboembolic disease.

Technology Process of {[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid

There total 1 articles about {[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ YM-60828 (179755-65-8)

Guidance literature: