3-Methyl-6,7-dihydro-5h-cyclopenta[b]pyridine

Base Information

• Chemical Name: 3-Methyl-6,7-dihydro-5h-cyclopenta[b]pyridine
• CAS No.: 28712-61-0
• Molecular Formula: C9H11 N
• Molecular Weight: 133.193
• Hs Code.: 2933990090
• European Community (EC) Number: 249-182-5
• DSSTox Substance ID: DTXSID20182872
• Nikkaji Number: J286.445B
• Wikidata: Q83053571
• Mol file: 28712-61-0.mol

Synonyms:3-methyl-6,7-dihydro-5h-cyclopenta[b]pyridine;28712-61-0;6,7-Dihydro-3-methyl-5H-1-pyrindine;EINECS 249-182-5;SCHEMBL11961587;DTXSID20182872

Chemical Property of 3-Methyl-6,7-dihydro-5h-cyclopenta[b]pyridine

Chemical Property:

• Vapor Pressure: 0.183mmHg at 25°C
• Boiling Point: 218.7°Cat760mmHg
• Flash Point: 75.6°C
• PSA: 12.89000
• Density: 1.04g/cm³
• LogP: 1.87870
• Storage Temp.: 2-8°C
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 133.089149355
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

99% ^*data from raw suppliers

3-METHYL-6,7-DIHYDRO-5H-CYCLOPENTA[B]PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(CCC2)N=C1

Technology Process of 3-Methyl-6,7-dihydro-5h-cyclopenta[b]pyridine

There total 2 articles about 3-Methyl-6,7-dihydro-5h-cyclopenta[b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

methacrolein oxime (28051-68-5) + cyclopentanone (120-92-3) → 6,7-dihydro-3-methyl-5H-1-pyrindine (28712-61-0) + 1,2,3,5,6,7-hexahydrodicyclopenta[b,e]pyridine (34421-99-3)

Guidance literature:

With piperidine hydrochloride; In toluene; at 200 ℃; for 2h; autoclave;

DOI:10.1055/s-1994-25526

Reference yield:

→ 6,7-dihydro-3-methyl-5H-1-pyrindine (28712-61-0)

Guidance literature:

3-Methyl-octahydro-1.5-pyrindin, Dehydrierung an Pd/C <310grad>;

upstream raw materials:

methacrolein oxime

cyclopentanone