1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide

Base Information

• Chemical Name: 1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide
• CAS No.: 148312-54-3
• Molecular Formula: C₁₂H₁₇N₅O₂S
• Molecular Weight: 295.365
• DSSTox Substance ID: DTXSID20163964
• Wikidata: Q83032969
• ChEMBL ID: CHEMBL2402539
• Mol file: 148312-54-3.mol

Synonyms:N,4-Dicyclopropyl-6-(3-thiazolidinyl)-1,3,5-triazin-2-amine S,S-dioxide;1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide;2-Cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine S,S-dioxyde;148312-54-3;SCHEMBL8471230;CHEMBL2402539;DTXSID20163964;LS-154944

Chemical Property of 1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide

Chemical Property:

• Vapor Pressure: 1.69E-15mmHg at 25°C
• Boiling Point: 624.2°Cat760mmHg
• Flash Point: 331.3°C
• Density: 1.579g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 295.11029598
• Heavy Atom Count: 20
• Complexity: 471

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1C2=NC(=NC(=N2)N3CCS(=O)(=O)C3)NC4CC4

Technology Process of 1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide

There total 4 articles about 1,3,5-Triazin-2-amine, N,4-dicyclopropyl-6-(3-thiazolidinyl)-, S,S-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.7%

→ 2-cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine S,S-dioxide (148312-54-3)

Guidance literature:

Reference yield:

2-cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine (148312-53-2) → 2-cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine S,S-dioxide (148312-54-3)

Guidance literature:

With potassium sulfate; potassium hydrogensulfate; potassium peroxomonosulfate; In methanol; dichloromethane; water; Ambient temperature;

DOI:10.1016/S0968-0896(98)00266-1

Reference yield:

2,4-dichloro-6-cyclopropyl-<1,3,5>triazine (148312-23-6) → 2-cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine S,S-dioxide (148312-54-3)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃

2: dioxane / Heating

3: KHSO₅*KHSO₄*K₂SO₄ / CH₂Cl₂; methanol; H₂O / Ambient temperature

With potassium sulfate; potassium hydrogensulfate; potassium peroxomonosulfate; potassium carbonate; In 1,4-dioxane; methanol; dichloromethane; water;

DOI:10.1016/S0968-0896(98)00266-1

upstream raw materials:

2-cyclopropyl-4-cyclopropylamino-6-(3-thiazolidinyl)-1,3,5-triazine

2,4-dichloro-6-cyclopropyl-<1,3,5>triazine

2-chloro-4-cyclopropyl-6-cyclopropylamino-<1,3,5>triazine