3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl methoxy]phenoxy]propoxy]methyl]-, methyl ester

Base Information

Chemical Name:3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl methoxy]phenoxy]propoxy]methyl]-, methyl ester
CAS No.:845743-99-9
Molecular Formula:C28H29ClN2O6
Molecular Weight:525.001
Hs Code.:

3-Pyridinecarboxylic acid,
4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl
methoxy]phenoxy]propoxy]methyl]-, methyl ester

Synonyms:

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Chemical Property of 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl methoxy]phenoxy]propoxy]methyl]-, methyl ester

Chemical Property:

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Technology Process of 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl methoxy]phenoxy]propoxy]methyl]-, methyl ester

There total 3 articles about 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-[[3-[2-[(2S)-oxiranyl methoxy]phenoxy]propoxy]methyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 845743-98-8
methyl 4-(2-chlorophenyl)-5-cyano-2-{[3-(2-hydroxyphenoxy)propoxy]methyl}-6-methyl-1,4-dihydropyridine-3-carboxylate

: 115314-14-2
(2s)-(+)-glycidyl 3-nitrobenzenesulfonate

: 845743-99-9
methyl 4-(2-chlorophenyl)-5-cyano-6-methyl-2-({3-[2-(oxiran-2-ylmethoxy)phenoxy]propoxy}methyl)-1,4-dihydropyridine-3-carboxylate

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 48h;

Reference yield:

: methyl 4-(-5-cyano-6-methyl-2-({3-[2-(phenylmethoxy)phenoxy]propoxy}methy))-1,4-dihydyridine-3-carboxylate

: 845743-99-9
methyl 4-(2-chlorophenyl)-5-cyano-6-methyl-2-({3-[2-(oxiran-2-ylmethoxy)phenoxy]propoxy}methyl)-1,4-dihydropyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 5 % Pd/CaCO3 / methanol / 4 h

2: sodium hydroxide / 1,4-dioxane; water / 48 h / 20 °C

With sodium hydroxide; hydrogen; 5 % Pd/CaCO3; In 1,4-dioxane; methanol; water;

Reference yield:

: 89-98-5
2-chloro-benzaldehyde

: 845743-99-9
methyl 4-(2-chlorophenyl)-5-cyano-6-methyl-2-({3-[2-(oxiran-2-ylmethoxy)phenoxy]propoxy}methyl)-1,4-dihydropyridine-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / Heating / reflux

2: hydrogen / 5 % Pd/CaCO3 / methanol / 4 h

3: sodium hydroxide / 1,4-dioxane; water / 48 h / 20 °C

With sodium hydroxide; hydrogen; 5 % Pd/CaCO3; In 1,4-dioxane; methanol; ethanol; water;