Hydroxysanguinarine

Base Information Edit

Chemical Name:Hydroxysanguinarine
CAS No.:548-30-1
Molecular Formula:C20H13NO5
Molecular Weight:347.327
Hs Code.:
DSSTox Substance ID:DTXSID80203274
Nikkaji Number:J396.552J
Wikidata:Q27114637
Metabolomics Workbench ID:69837
ChEMBL ID:CHEMBL4785846
Mol file:548-30-1.mol

Synonyms:oxysanguinarine

Suppliers and Price of Hydroxysanguinarine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Oxysanguinarine
1mg
$ 120.00

Arctom
Oxysanguinarine
10mg
$ 268.00

Total 17 raw suppliers

Chemical Property of Hydroxysanguinarine Edit

Chemical Property:

Vapor Pressure:1.01E-15mmHg at 25°C
Melting Point:223-224 °C
Boiling Point:628.7°Cat760mmHg
PKA:-1.58±0.20(Predicted)
Flash Point:334.1°C
PSA：58.92000
Density:1.509g/cm³
LogP:3.30230
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:347.07937252
Heavy Atom Count:26
Complexity:599

Purity/Quality:

≥98% ^*data from raw suppliers

Oxysanguinarine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=CC3=CC4=C(C=C32)OCO4)C5=C(C1=O)C6=C(C=C5)OCO6
Description An a-naphthaphenanthridine alkaloid, this base occurs in the roots of Sanguinaria canadensis. It is separated from the remaining bases by chromatography and purified by crystallization from CHC13 followed by sublimation in a high vacuum. It is optically inactive and may also be prepared by oxidation of sanguinarine nitrate by potassium ferricyanide in alkaline solution. No salts of this alkaloid have been prepared.
Uses Hydroxysanguinarine can be used to treat coronavirus infection.

Technology Process of Hydroxysanguinarine

There total 56 articles about Hydroxysanguinarine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: C₂₀H₁₅NO₅

: 548-30-1
oxysanguinarine

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; for 2h; Inert atmosphere; Reflux;
DOI:10.1039/c0ob01208d

Reference yield: 90.0%

: 1620903-00-5
6-bromo-2,3-methylenedioxy-N-methyl-N-(6,7-methylenedioxynaphthalen-1-yl)benzamide

: 548-30-1
oxysanguinarine

Guidance literature:: With trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II); silver carbonate; In N,N-dimethyl-formamide; at 160 ℃; for 22h; Sealed tube; Inert atmosphere;
DOI:10.1021/jo5014492