D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate)

Base Information

• Chemical Name: D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate)
• CAS No.: 214282-36-7
• Molecular Formula: C₄₁H₈₁O₁₉P₃
• Molecular Weight: 971.004
• Mol file: 214282-36-7.mol

Synonyms:D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate)

Chemical Property of D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 995.9°Cat760mmHg
• Flash Point: 556.1°C
• PSA: 332.00000
• Density: 1.27g/cm³
• LogP: 7.95830

Purity/Quality:

99% ^*data from raw suppliers

L-ALPHA-PHOSPHATIDYL-D-MYO-INOSITOL-3,5-DIPHOSPHATE, DIPALMITOYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate)

There total 2 articles about D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,5-bis(dihydrogen phosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Hexadecanoic acid (S)-2-{benzyloxy-[(1R,2S,3S,4R,5S,6R)-2,4-bis-benzyloxy-3,5-bis-(bis-benzyloxy-phosphoryloxy)-6-hydroxy-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester → dipalmitoyl phosphatidyl-D-myo-inositol 3,5-bisphosphate (214282-36-7)

Guidance literature:

With hydrogen; sodium hydrogencarbonate; palladium; In ethanol; water; at 23 ℃; for 6h; under 2689.17 Torr;

DOI:10.1016/S0040-4039(00)00465-2

Reference yield:

Hexadecanoic acid (S)-2-{benzyloxy-[(1S,2R,3R,4S,5S,6R)-3,5-bis-(bis-benzyloxy-phosphoryloxy)-2,4,6-trihydroxy-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester → dipalmitoyl phosphatidyl-D-myo-inositol 3,5-bisphosphate (214282-36-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; ethyl acetate; at 20 ℃;

DOI:10.1246/cl.2003.724

Refernces

• 1、 Falck,Krishna, U. Murali,Katipally, Kishta Reddy,Capdevila, Jorge H.,Ulug, Emin T.. "Concise syntheses of L-α-phosphatidyl-D-myo-inositol 3-phosphate (3- PIP), 5-phosphate (5-PIP), and 3,5-bisphosphate (3,5-PIP2)". . p. 4271 - 4275. Retrieved 2007/10/03.