Eltenac

Base Information

• Chemical Name: Eltenac
• CAS No.: 72895-88-6
• Molecular Formula: C12H9 Cl2 N O2 S
• Molecular Weight: 302.181
• Hs Code.: 2934999090
• European Community (EC) Number: 688-480-3
• UNII: A153L3JA99
• DSSTox Substance ID: DTXSID30223184
• Nikkaji Number: J33.124D
• Wikidata: Q27273482
• NCI Thesaurus Code: C77358
• ChEMBL ID: CHEMBL2104561
• Mol file: 72895-88-6.mol

Synonyms:eltenac;Telzenac

Chemical Property of Eltenac

Chemical Property:

• Vapor Pressure: 8.76E-08mmHg at 25°C
• Boiling Point: 419.4°C at 760 mmHg
• PKA: 4.13±0.10(Predicted)
• Flash Point: 207.4°C
• PSA: 77.57000
• Density: 1.539g/cm³
• LogP: 4.49860
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 300.9731051
• Heavy Atom Count: 18
• Complexity: 296

Purity/Quality:

NLT 98% ^*data from raw suppliers

Eltenac ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)NC2=CSC=C2CC(=O)O)Cl
• Uses: Eltenac is a nonsteroidal anti-inflammatory drug. A nonsteroidal anti-inflammatory drug

Technology Process of Eltenac

There total 3 articles about Eltenac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2,6-dichloroanilino)-3-thiophenacetic acid methyl ester → 4-(2,6-dichloroanilino)-3-thiopheneacetic acid (72895-88-6)

Guidance literature:

With sodium hydroxide; In methanol; di-isopropyl ether; water;

Reference yield:

4-(2,6-dichloroanilino)-3-thiophenacetic acid tert.-butyl ester → 4-(2,6-dichloroanilino)-3-thiopheneacetic acid (72895-88-6)

Guidance literature:

With toluene-4-sulfonic acid; In toluene;

Reference yield:

4-(2,6-dichloroanilino)-3-thiophenacetic acid benzyl ester → 4-(2,6-dichloroanilino)-3-thiopheneacetic acid (72895-88-6)

Guidance literature:

In sodium hydroxide; palladium-on-active charcoal; acetic acid; ethyl acetate;