1-Boc-4-(4-Bromo-benzylamino)-piperidine

Base Information

Chemical Name:1-Boc-4-(4-Bromo-benzylamino)-piperidine
CAS No.:846605-66-1
Molecular Formula:C17H25BrN2O2
Molecular Weight:369.302
Hs Code.:2933399090
DSSTox Substance ID:DTXSID10693164
Wikidata:Q82622185
Mol file:846605-66-1.mol

Synonyms:846605-66-1;1-Boc-4-(4-Bromo-benzylamino)-piperidine;tert-Butyl 4-((4-bromobenzyl)amino)piperidine-1-carboxylate;tert-butyl 4-[(4-bromophenyl)methylamino]piperidine-1-carboxylate;tert-Butyl 4-(4-bromobenzylamino)piperidine-1-carboxylate;2-Thienyldisulfide;4-(4-Bromo-benzylamino)-piperidine-1-carboxylic acid tert-butyl ester;SCHEMBL5013239;DTXSID10693164;FIMXQBKKMLARJD-UHFFFAOYSA-N;KS-5837;1-boc-4-(4-bromobenzylamino)piperidine;1-Piperidinecarboxylic acid, 4-[[(4-bromophenyl)methyl]amino]-,1,1-dimethylethyl ester;CS-0362678;tert-Butyl4-((4-bromobenzyl)amino)piperidine-1-carboxylate;TERT-BUTYL 4-{[(4-BROMOPHENYL)METHYL]AMINO}PIPERIDINE-1-CARBOXYLATE

Suppliers and Price of 1-Boc-4-(4-Bromo-benzylamino)-piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1-Boc-4-(4-Bromo-benzylamino)-piperidine 95
10g
$ 1833.00

American Custom Chemicals Corporation
1-BOC-4-(4-BROMO-BENZYLAMINO)-PIPERIDINE 95.00%
5MG
$ 495.91

Total 3 raw suppliers

Chemical Property of 1-Boc-4-(4-Bromo-benzylamino)-piperidine

Chemical Property:

Boiling Point:443.3±40.0 °C(Predicted)
PKA:8.97±0.20(Predicted)
PSA：41.57000
Density:1.30±0.1 g/cm3(Predicted)
LogP:4.26700
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:368.10994
Heavy Atom Count:22
Complexity:354

Purity/Quality:

99% ^*data from raw suppliers

1-Boc-4-(4-Bromo-benzylamino)-piperidine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)NCC2=CC=C(C=C2)Br

Technology Process of 1-Boc-4-(4-Bromo-benzylamino)-piperidine

There total 2 articles about 1-Boc-4-(4-Bromo-benzylamino)-piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 846605-66-1
4-(4-bromobenzylamino)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:

Reference yield:

: 189819-75-8
4-amino-1-(t-butoxycarbonyl)piperidine monohydrochloride

: 1122-91-4
4-bromo-benzaldehyde

: 846605-66-1
4-(4-bromobenzylamino)piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 4-amino-1-(t-butoxycarbonyl)piperidine monohydrochloride; 4-bromo-benzaldehyde; With N-ethyl-N,N-diisopropylamine; In methanol; for 4h; Heating / reflux;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.25h; Product distribution / selectivity;

Reference yield: 86.0%

: 24472-57-9
5-pentyl-pyridine-2-carboxylic acid

: 846605-66-1
4-(4-bromobenzylamino)piperidine-1-carboxylic acid tert-butyl ester

: 888944-53-4
4-[(4-bromo-benzyl)-(5-pentyl-pyridine-2-carbonyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: 5-pentyl-pyridine-2-carboxylic acid; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.0833333h;

4-(4-bromobenzylamino)piperidine-1-carboxylic acid tert-butyl ester; In dichloromethane; at 20 ℃; for 1.5h;