Ferrioxamine E

Base Information

• Chemical Name: Ferrioxamine E
• CAS No.: 20008-20-2
• Molecular Formula: C27H45FeN6O9
• Molecular Weight: 653.53
• DSSTox Substance ID: DTXSID80173822
• Mol file: 20008-20-2.mol

Synonyms:ferrioxamine E

Chemical Property of Ferrioxamine E

Chemical Property:

• PSA: 227.88000
• LogP: 1.81820
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 0
• Exact Mass: 653.259738
• Heavy Atom Count: 43
• Complexity: 764

Purity/Quality:

97% ^*data from raw suppliers

Ferrioxamine E from Streptomyces antibioticus suitable for microbiology, ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CC1)[O-])[O-])[O-].[Fe+3]
• Description: Ferrioxamine E is a bacterial siderophore produced by a variety of bacteria including S. glaucescens, M. luteus, and P. mendocina. Ferrioxamines, including ferrioxamine E, are the sole iron source for Salmonella, and have been used as growth enriching agents in the detection of Salmonella in food and industrial applications.

Technology Process of Ferrioxamine E

There total 2 articles about Ferrioxamine E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H51FeN6O12 → ferrioxamine E (20008-20-2)

Guidance literature:

With diphenyl phosphoryl azide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 168h; Inert atmosphere;

DOI:10.1021/acs.inorgchem.5b00141

Reference yield:

4-((5-aminopentyl)(hydroxy)amino)-4-oxobutanoic acid → ferrioxamine E (20008-20-2)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 1 h / 20 °C

2: triethylamine; diphenyl phosphoryl azide / N,N-dimethyl-formamide / 168 h / 20 °C / Inert atmosphere

With diphenyl phosphoryl azide; triethylamine; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/acs.inorgchem.5b00141