Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester
CAS No.:847199-90-0
Molecular Formula:C16H22N2O2
Molecular Weight:274.363
Hs Code.:

Synonyms:tert-butyl (R)-1-(1H-indol-3-yl)propan-2-ylcarbamate;[(R)-2-(1H-Indol-3-yl)-1-methyl-ethyl]-carbamic acid tert-butyl ester;

Suppliers and Price of Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Chemenu
(R)-tert-butyl(1-(1H-indol-3-yl)propan-2-yl)carbamate 95%+
50g
$ 1094.00

Total 15 raw suppliers

Chemical Property of Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester

Chemical Property:

PSA：54.12000
LogP:4.01450

Purity/Quality:

99%, ^*data from raw suppliers

(R)-tert-butyl(1-(1H-indol-3-yl)propan-2-yl)carbamate 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester

There total 13 articles about Carbamic acid, [(1R)-2-(1H-indol-3-yl)-1-methylethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 7795-52-0,304-54-1
(-)-alpha-Methyltryptamine

: 847199-90-0
tert-butyl (R)-(1-(1H-indol-3-yl)propan-2-yl)carbamate

Guidance literature:: In chloroform; at 20 ℃;
DOI:10.1016/j.bmc.2004.10.032

Reference yield: 70.0%

: 120-72-9
indole

: 454248-53-4
(R)-4-methyl-2,2-dioxo-1,2,3-oxathiazolidine-3-carboxylic acid tert butyl ester

: 847199-90-0
tert-butyl (R)-(1-(1H-indol-3-yl)propan-2-yl)carbamate

Guidance literature:: indole; With methylmagnesium chloride; copper(l) chloride; In tetrahydrofuran; dichloromethane; at 0 ℃; for 1.16667h; Inert atmosphere;

(R)-4-methyl-2,2-dioxo-1,2,3-oxathiazolidine-3-carboxylic acid tert butyl ester; In tetrahydrofuran; dichloromethane; at -20 ℃; for 18.5h; regioselective reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.8b02335

Reference yield: 70.0%

: 847199-90-0
tert-butyl (R)-(1-(1H-indol-3-yl)propan-2-yl)carbamate

Guidance literature:: With methylmagnesium chloride; copper(l) chloride; In tetrahydrofuran; dichloromethane; at 0 ℃; for 1.16667h; Inert atmosphere;

In tetrahydrofuran; dichloromethane; at -20 ℃; for 18h; Inert atmosphere;