Methyldihydrocodeinone

Base Information

Chemical Name:Methyldihydrocodeinone
CAS No.:63868-37-1
Molecular Formula:C19H23 N O3
Molecular Weight:313.397
Hs Code.:
DSSTox Substance ID:DTXSID60980576
Nikkaji Number:J72.600A
Wikidata:Q76311133
Mol file:63868-37-1.mol

Synonyms:Methyldihydrocodeinone;Codeinone, methyldihydro-;BRN 0046357;63868-37-1;Morphinan-6-one, 5-beta,17-dimethyl-4,5-alpha-epoxy-3-methoxy-;DTXSID60980576;LS-92140;3-Methoxy-5,17-dimethyl-4,5-epoxymorphinan-6-one;5beta,17-Dimethyl-4,5alpha-epoxy-3-methoxymorphinan-6-one;Morphinan-6-one, 4,5-epoxy-3-methoxy-5,17-dimethyl-, (5.alpha.)-

Suppliers and Price of Methyldihydrocodeinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyldihydrocodeinone

Chemical Property:

Vapor Pressure:1.48E-08mmHg at 25°C
Boiling Point:457.5°Cat760mmHg
Flash Point:230.5°C
PSA：38.77000
Density:1.28g/cm³
LogP:2.26130
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:313.16779360
Heavy Atom Count:23
Complexity:551

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12C(=O)CCC3C14CCN(C3CC5=C4C(=C(C=C5)OC)O2)C
Isomeric SMILES:C[C@]12C(=O)CC[C@@H]3[C@]14CCN([C@@H]3CC5=C4C(=C(C=C5)OC)O2)C

Technology Process of Methyldihydrocodeinone

There total 7 articles about Methyldihydrocodeinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 118112-52-0
5-methylcodeinone

: 63868-37-1
5-methyldihydrocodeinone

Guidance literature:: With L-Selectride; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;
DOI:10.1021/jo00346a037

Reference yield: 83.0%

: 118112-52-0
(-)-5β-methylcodeinone

: 63868-37-1
5β-methyl-dihydrocodeinone

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 10h; under 1810.07 Torr;
DOI:10.2174/157340613804488323

Reference yield:

: 80583-35-3
5β-methylthebaine

: 63868-37-1
5-methyldihydrocodeinone

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / H₂ / 10percent PdCl₂/charcoal / ethanol / 1 h / 760 Torr

2: 291 mg / 10percent HCl / H₂O / 0.17 h / Heating

With hydrogenchloride; hydrogen; pyrographite; palladium dichloride; In ethanol; water;
DOI:10.1021/jo00346a037