Pyridino(1,2-a)imidazo(5,4-b)indole

Base Information

• Chemical Name: Pyridino(1,2-a)imidazo(5,4-b)indole
• CAS No.: 60067-39-2
• Molecular Formula: C₁₃H₉N₃
• Molecular Weight: 207.235
• NSC Number: 363438
• DSSTox Substance ID: DTXSID70208793
• Wikidata: Q83082944
• ChEMBL ID: CHEMBL1983842
• Mol file: 60067-39-2.mol

Synonyms:1,2-PIID;pyridino(1,2-a)imidazo(5,4-b)indole

Chemical Property of Pyridino(1,2-a)imidazo(5,4-b)indole

Chemical Property:

• Boiling Point: 397oC at 760 mmHg
• Flash Point: 193.9oC
• PSA: 33.09000
• Density: 1.39g/cm3
• LogP: 2.96880
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 207.079647300
• Heavy Atom Count: 16
• Complexity: 280

Purity/Quality:

99% ^*data from raw suppliers

5H-Pyrido[2',1':2,3]imidazo[4,5-b]indole 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)N4C=CC=CC4=N3

Technology Process of Pyridino(1,2-a)imidazo(5,4-b)indole

There total 4 articles about Pyridino(1,2-a)imidazo(5,4-b)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5-benzyl-5H-pyrido[2′,1′:2,3]imidazo[4,5-b]indole → pyridino<1,2-a>imidazo<5,4-b>indole (60067-39-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h;

Reference yield:

C20H16BrN3 → pyridino<1,2-a>imidazo<5,4-b>indole (60067-39-2)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; caesium carbonate / 1,4-dioxane / 12 h / Inert atmosphere; Reflux

2: hydrogen; palladium on activated charcoal / ethanol / 18 h / 20 °C

With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; palladium on activated charcoal; hydrogen; caesium carbonate; In 1,4-dioxane; ethanol;

Reference yield:

→ 5H-pyrido[2',1':2,3]imidiazo-[4,5-b]indole + pyridino<1,2-a>imidazo<5,4-b>indole (60067-39-2)

Guidance literature:

Refernces

• 1、 -. "MULTICYCLIC COMPOUND HAVING NITROGEN AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME". . . Retrieved 2016/10/09.