DMEQ-TAD

Base Information

• Chemical Name: DMEQ-TAD
• CAS No.: 132788-52-4
• Molecular Formula: C15H15 N5 O5
• Molecular Weight: 345.31
• Hs Code.: 2933990090
• Mol file: 132788-52-4.mol

Synonyms:DMEQ-TAD

Chemical Property of DMEQ-TAD

Chemical Property:

• Vapor Pressure: 1.85E-11mmHg at 25°C
• Melting Point: >200?C (dec.)
• Boiling Point: 533.5°Cat760mmHg
• Flash Point: 276.4°C
• PSA: 115.45000
• Density: 1.52g/cm³
• LogP: 0.31010
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat

Purity/Quality:

97% ^*data from raw suppliers

DMEQ-TAD ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: DMEQ-TAD is a reagent for fluorescence-labeling of Vitamin D and its use in assaying Vitamin D metabolites.

Technology Process of DMEQ-TAD

There total 6 articles about DMEQ-TAD which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-[2-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-ethyl]-[1,2,4]triazolidine-3,5-dione (132788-54-6) → 4-<2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl>-1,2,4-triazoline-3,5-dione (132788-52-4)

Guidance literature:

With [bis(acetoxy)iodo]benzene; In dichloromethane; Ambient temperature;

DOI:10.1039/c39900001416

Reference yield:

3-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-propionic acid (132788-56-8) → 4-<2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl>-1,2,4-triazoline-3,5-dione (132788-52-4)

Guidance literature:

Multi-step reaction with 5 steps

1: diphenylphosphoryl azide (DPPA), Et₃N / dimethylformamide

2: benzene / 1 h / Heating

3: benzene / 0.5 h / Heating

4: 81 percent / K₂CO₃ / ethanol / 6 h / Heating

5: 100 percent / PhI(OAc)2 / CH₂Cl₂ / Ambient temperature

With [bis(acetoxy)iodo]benzene; diphenylphosphoranyl azide; potassium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide; benzene;

DOI:10.1039/c39900001416

Reference yield:

3-(2-Isocyanato-ethyl)-6,7-dimethoxy-1-methyl-1H-quinoxalin-2-one → 4-<2-(6,7-dimethoxy-4-methyl-3-oxo-3,4-dihydroquinoxalyl)ethyl>-1,2,4-triazoline-3,5-dione (132788-52-4)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene / 0.5 h / Heating

2: 81 percent / K₂CO₃ / ethanol / 6 h / Heating

3: 100 percent / PhI(OAc)2 / CH₂Cl₂ / Ambient temperature

With [bis(acetoxy)iodo]benzene; potassium carbonate; In ethanol; dichloromethane; benzene;

DOI:10.1039/c39900001416

upstream raw materials:

4-[2-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-ethyl]-[1,2,4]triazolidine-3,5-dione

3-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-propionic acid

3-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-propionyl azide

C₁₇H₂₃N₅O₆

Downstream raw materials:

2-[2-(6,7-Dimethoxy-4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-ethyl]-5-hydroxymethyl-6-methyl-8-[(1E,3E)-2-methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-buta-1,3-dienyl]-5,8-dihydro-[1,2,4]triazolo[1,2-a]pyridazine-1,3-dione

Refernces