Chemical Property of Fucoidan
Chemical Property:
- Appearance/Colour:Yellow brown fine powder
- PSA：121.67000
- LogP:-0.21580
- Storage Temp.:Refrigerator
- Solubility.:H2O: soluble10mg/mL, clear to hazy, faintly yellow to brownish-y
- Purity/Quality:
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1%-101.0% *data from raw suppliers
Fucoidan *data from reagent suppliers
Safty Information:
- Pictogram(s):
C
- Hazard Codes:C
- Statements:
34
- Safety Statements:
26-27-36/37/39-45
- MSDS Files:
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SDS file from LookChem
Useful:
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Description
Fucoidan is a polysaccharide largely made up of l-fucose and sulfate groups. Fucoidan is favorable worldwide, especially amongst the food and pharmaceutical industry as a consequence of its promising therapeutic effects. Its applaudable biological functions are ascribed to its unique biological structure. Classical bioactivities associated with fucoidan include anti-oxidant, anti-tumor, anti-coagulant, anti-thrombotic, immunoregulatory, anti-viral and anti-inflammatory effects.
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Uses
Fucoidan can be used as a biological response modifier and as a potential therapeutic agent with a wide range of biological activities. It can be used to study its pharmacokinetics, safety, efficacy and delivery methods as a potential anticancer, anti-immune and anti-inflammatory agent. Fucoidan is a water-soluble polysaccharide; it gives highly viscous solutions. The most important application of fucoidan is in food – fucoidan containing food and supplements are very popular on the Japanese market. Raw fucoidan materials are also used for cosmetics because the product is directly adsorbed by the human skin with the following effects: whitening, preserving moisture, removing freckles.Fucoidan has also important medical applications. The higher the sulfation, the higher its therapeutic potential. The role of fucoidan is as modulator of coagulation, as an alternative to the anticoagulant heparin, and many other biological activities such as anti-inflammation, anticell proliferation, and antiadhesion and antiviral infection, as fertilizer, anticoagulant, antitumor, antiviral agents. In addition, they act as ligands for selectins, protect gastric mucosa against proteolytic activity of gastric juice, block mammalian fertilization, etc. Fucoidan is a new anti-tumor drug or an adjuvant drug used in combination with anti-tumor drugs, which can exert anti-cancer effects directly through cell cycle arrest and induction of apoptosis, or indirectly by activating natural killer cells and macrophages to kill cancer cells.
