Hecogenin acetate

Base Information Edit

Chemical Name:Hecogenin acetate
CAS No.:915-35-5
Deprecated CAS:27040-14-8,11034-95-0,72341-18-5
Molecular Formula:C29H44 O5
Molecular Weight:472.665
Hs Code.:
European Community (EC) Number:213-021-7
NSC Number:15489
UNII:5K0WKD513R
Nikkaji Number:J195.206D
Wikidata:Q27262471
Metabolomics Workbench ID:199099
ChEMBL ID:CHEMBL2332640
Mol file:915-35-5.mol

Synonyms:(3beta,5alpha,25R)-12-oxospirostan-3-yl acetate;hecogenin acetate

Suppliers and Price of Hecogenin acetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Hecogenin Acetate
250mg
$ 425.00

TRC
HecogeninAcetate,90%
250mg
$ 130.00

TCI Chemical
Hecogenin Acetate >90.0%(GC)
1g
$ 56.00

TCI Chemical
Hecogenin Acetate >90.0%(GC)
5g
$ 146.00

Sigma-Aldrich
Hecogenin acetate ≥90%
25g
$ 558.00

ChemScene
Hecogenin acetate
100mg
$ 80.00

Cayman Chemical
Hecogenin Acetate ≥98%
10g
$ 245.00

Cayman Chemical
Hecogenin Acetate ≥98%
5g
$ 135.00

Cayman Chemical
Hecogenin Acetate ≥98%
1g
$ 49.00

American Custom Chemicals Corporation
HECOGENIN ACETATE 98.00%
100G
$ 2910.60

Total 20 raw suppliers

Chemical Property of Hecogenin acetate Edit

Chemical Property:

Vapor Pressure:1.82E-12mmHg at 25°C
Melting Point:246-248 °C (dec.)(lit.)
Refractive Index:-4 ° (C=1, Dioxane)
Boiling Point:557.5°Cat760mmHg
Flash Point:264.7°C
PSA：61.83000
Density:1.15g/cm³
LogP:5.54360
Storage Temp.:Refrigerator
Solubility.:Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, He
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:472.31887450
Heavy Atom Count:34
Complexity:871

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hecogenin Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

Useful:

Canonical SMILES:CC1CCC2(C(C3C(O2)CC4C3(C(=O)CC5C4CCC6C5(CCC(C6)OC(=O)C)C)C)C)OC1
Isomeric SMILES:C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(C(=O)C[C@H]5[C@H]4CC[C@@H]6[C@@]5(CC[C@@H](C6)OC(=O)C)C)C)C)OC1
Description Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Uses Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.

Technology Process of Hecogenin acetate

There total 8 articles about Hecogenin acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%