1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine

Base Information

Chemical Name:1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine
CAS No.:847774-93-0
Molecular Formula:C13H16ClN3
Molecular Weight:249.743
Hs Code.:
European Community (EC) Number:840-421-4

Synonyms:1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine;SCHEMBL4494427;AKOS005831812;CS-0259945;EN300-7436023;847774-93-0

Suppliers and Price of 1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:249.1032752
Heavy Atom Count:17
Complexity:264

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)N1C(=CC(=N1)C2=CC(=CC=C2)Cl)N

Technology Process of 1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine

There total 2 articles about 1-Tert-butyl-3-(3-chlorophenyl)-1h-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 21667-62-9
3-chlorobenzoylacetonitrile

: 7400-27-3
tertbutylhydrazine hydrochloride

: 847774-93-0
1-(tert-butyl)-3-(3-chlorophenyl)-1H-pyrazol-5-amine

Guidance literature:: With triethylamine; In methanol; at 120 ℃; for 1.5h; Microwave irradiation; Sealed tube;
DOI:10.1021/acs.jmedchem.0c01777

Reference yield:

: 847774-93-0
1-(tert-butyl)-3-(3-chlorophenyl)-1H-pyrazol-5-amine

Guidance literature:

Reference yield:

: 847774-93-0
1-(tert-butyl)-3-(3-chlorophenyl)-1H-pyrazol-5-amine

: (2,4-bis(benzyloxy)-6-bromophenyl)(isoindolin-2-yl)methanone

: C₄₂H₃₉ClN₄O₃

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium phenoxide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 170 ℃; for 2h; Inert atmosphere; Sealed tube; Microwave irradiation;
DOI:10.1021/acs.jmedchem.0c01777