1H-Indole-1-carboxylic acid, 5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]- 1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1H-Indole-1-carboxylic acid, 5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]- 1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester
CAS No.:848357-60-8
Molecular Formula:C31H40N4O4S
Molecular Weight:564.749
Hs Code.:

1H-Indole-1-carboxylic acid,
5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]-
1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester

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Chemical Property of 1H-Indole-1-carboxylic acid, 5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]- 1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester

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Technology Process of 1H-Indole-1-carboxylic acid, 5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]- 1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester

There total 1 articles about 1H-Indole-1-carboxylic acid, 5-[[(cyclohexylmethyl)amino]methyl]-2-[1-[(1,1-dimethylethoxy)carbonyl]- 1H-thieno[3,2-c]pyrazol-3-yl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 848357-11-9
2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-formylindole-1-carboxylic acid tert-butyl ester

: 3218-02-8
cyclohexylmethylamine

: 3-{5-[(cyclohexylmethylamino)methyl]-1H-indol-2-yl}thieno[3,2-c]pyrazole-1-carboxylic acid tert-butyl ester

: 5-[(cyclohexylmethylamino)methyl]-2-(1H-thieno[3,2-c]pyrazol-3-yl)indole-1-carboxylic acid tert-butyl ester

: 848357-60-8
2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-[(cyclohexylmethylamino)methyl]indole-1-carboxylic acid tert-butyl ester

Guidance literature:: With acetic acid; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

: 3-{5-[(cyclohexylmethylamino)methyl]-1H-indol-2-yl}thieno[3,2-c]pyrazole-1-carboxylic acid tert-butyl ester

: 5-[(cyclohexylmethylamino)methyl]-2-(1H-thieno[3,2-c]pyrazol-3-yl)indole-1-carboxylic acid tert-butyl ester

: 848357-60-8
2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-[(cyclohexylmethylamino)methyl]indole-1-carboxylic acid tert-butyl ester

: cyclohexylmethyl-[2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-5-ylmethyl]amine

Guidance literature:: 3-{5-[(cyclohexylmethylamino)methyl]-1H-indol-2-yl}thieno[3,2-c]pyrazole-1-carboxylic acid tert-butyl ester; 5-[(cyclohexylmethylamino)methyl]-2-(1H-thieno[3,2-c]pyrazol-3-yl)indole-1-carboxylic acid tert-butyl ester; 2-(1-tert-butoxycarbonyl-1H-thieno[3,2-c]pyrazol-3-yl)-5-[(cyclohexylmethylamino)methyl]indole-1-carboxylic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

With ammonia; In methanol; at 20 ℃;