acyclovir triphosphate

Base Information

• Chemical Name: acyclovir triphosphate
• CAS No.: 66341-18-2
• Molecular Formula: C8H14N5O12P3
• Molecular Weight: 465.147
• Mol file: 66341-18-2.mol

Synonyms:Aciclvir-triphosphate;Acycloguanosine triphosphate;Aciclovir-triphosphate;acyclovir-triphosphate;AcycloGTP;

Chemical Property of acyclovir triphosphate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 881.4°Cat760mmHg
• Flash Point: 486.8°C
• PSA: 288.07000
• Density: 2.42g/cm³
• LogP: -0.39960

Purity/Quality:

98% ^*data from raw suppliers

ACYCLOVIR TRIPHOSPHATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of acyclovir triphosphate

There total 1 articles about acyclovir triphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acyclovir-5'-phosphorodichloridate (852842-29-6) → Acyclovir triphosphate (66341-18-2)

Guidance literature:

With tri(n-butyl)ammonium pyrophosphate; In various solvent(s); at 20 ℃; for 0.5h;

DOI:10.1002/anie.200702217

Reference yield:

3-phosphoglyceric acid (820-11-1,3443-58-1,73358-94-8,111614-09-6) + Acyclovir triphosphate (66341-18-2) → glyceric acid 1,3-biphosphate (38168-82-0,1981-49-3) + acyclovir diphosphate

Guidance literature:

With human phosphoglycerate kinase; magnesium chloride; diothiothreitol; In various solvent(s); at 25 ℃; pH=7.5; Enzyme kinetics;

DOI:10.1016/j.bcp.2004.06.012

upstream raw materials:

acyclovir-5'-phosphorodichloridate

Downstream raw materials:

glyceric acid 1,3-biphosphate

Refernces