alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid

Base Information

Chemical Name:alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid
CAS No.:60723-72-0
Molecular Formula:C₁₇H₁₅NO₃
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID50976165
ChEMBL ID:CHEMBL3275259

Synonyms:BRN 1136354;alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid;7-Benzoxazoleacetic acid, alpha-methyl-2-(4-methylphenyl)-;60723-72-0;CHEMBL3275259;DTXSID50976165;2-[2-(4-methylphenyl)-1,3-benzoxazol-7-yl]propanoic acid;LS-42101

Suppliers and Price of alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid

Chemical Property:

Vapor Pressure:2.82E-08mmHg at 25°C
Boiling Point:433.3°Cat760mmHg
Flash Point:215.9°C
Density:1.245g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:378

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=CC=CC(=C3O2)C(C)C(=O)O

Technology Process of alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid

There total 2 articles about alpha-Methyl-2-(4-methylphenyl)-7-benzoxazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 60723-72-0
2-(2-p-tolyl-benzooxazol-7-yl)-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: NaOEt, KI / ethanol

2: 170 - 200 °C

3: Zn, aq. NH₄Cl / ethanol

4: (i) Py, (ii) KIO₄, aq. KMnO₄, acetone

With sodium ethanolate; ammonium chloride; potassium iodide; zinc; In ethanol;
DOI:10.1021/jm00211a039