Brevicompanine B

Base Information

Chemical Name:Brevicompanine B
CAS No.:215121-47-4
Molecular Formula:C22H29N3O2
Molecular Weight:367.48
Hs Code.:
Mol file:215121-47-4.mol

Synonyms:

Suppliers and Price of Brevicompanine B

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Brevicompanine B
1mg
$ 165.00

Cayman Chemical
Brevicompanine B
5mg
$ 495.00

AK Scientific
9-(2-Methylbut-3-en-2-yl)-4-(2-methylpropyl)-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione
1mg
$ 322.00

Total 4 raw suppliers

Chemical Property of Brevicompanine B

Chemical Property:

PSA：64.93000
LogP:3.38540

Purity/Quality:

96% ^*data from raw suppliers

Brevicompanine B ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Brevicompanine B is a fungal metabolite originally isolated from P. brevicompactum that has plant growth and circadian rhythm regulatory activity. It inhibits hypocotyl elongation in lettuce seedlings when used at a concentration of 100 mg/L but does not inhibit elongation in rice seedlings at a concentration of 300 mg/L. Brevicompanine B (100 μM) inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various genes involved in the regulation of plant circadian rhythm. It is active against P. falciparum with an IC50 value of 35 mg/ml.
Uses Brevicompanine B is a diketopiperazine-related metabolite produced by Penicillium and Aspergillus species. Brevicompanine B is active against the malaria parasite, Plasmodium falciparum, and shows pronounced plant growth regulatory activity but is devoid of antifungal or antibacterial activity.

Technology Process of Brevicompanine B

There total 15 articles about Brevicompanine B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: (-)-(2S,3aR,8aS)-methyl 1-((R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoyl)-3a-(2-methylbut-3-en-2-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylate

: 215121-47-4
(-)-brevicompanine B

Guidance literature:: With diethylamine; In tetrahydrofuran; at 0 - 22 ℃; for 14h; Inert atmosphere;
DOI:10.1021/ja509893s

Reference yield:

: (R)-2-{[(2S,3aR,8aR)-3a-(1,1-Dimethyl-allyl)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carbonyl]-amino}-4-methyl-pentanoic acid

: 215121-47-4
brevicompanine B

Guidance literature:: With O-benzotriazol-1-yl-N,N,N',N'-tetramethyluronium F₆PO₄; In dichloromethane; at 20 ℃; for 14h;
DOI:10.3987/com-00-s(i)51

Reference yield:

: (S)-2-{[(2S,3aR,8aR)-3a-(1,1-Dimethyl-allyl)-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carbonyl]-amino}-4-methyl-pentanoic acid

: 215121-47-4
(2S,10aS,5aS,4aS)-5a-(1,1-dimethylprop-2-enyl)-2-(2-methylpropyl)-1,2,3,4,4a,5,5a,10a-octahydro-10H-pyrazino[1',2':1,2]pyrrolo[4,5-b]indole-1,4-dione

Guidance literature:: With O-benzotriazol-1-yl-N,N,N',N'-tetramethyluronium F₆PO₄; In dichloromethane; at 20 ℃; for 14h;
DOI:10.3987/com-00-s(i)51