3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid

Base Information

• Chemical Name: 3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid
• CAS No.: 63021-00-1
• Molecular Formula: C16H18O3
• Molecular Weight: 258.34
• DSSTox Substance ID: DTXSID80978930
• Nikkaji Number: J71.048B
• Wikidata: Q82964419
• Mol file: 63021-00-1.mol

Synonyms:3-(6-methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid;63021-00-1;Dimethyl ethyl allenolic acid methyl ether;BRN 3322557;Acide dimethyl-ethyl-allenolique ether methylique [French];Propionic acid, alpha,alpha-dimethyl-2-(6-methoxynaphthyl)-;Acide dimethyl-ethyl-allenolique ether methylique;3-10-00-01123 (Beilstein Handbook Reference);DTXSID80978930

Chemical Property of 3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid

Chemical Property:

• Vapor Pressure: 5.6E-08mmHg at 25°C
• Refractive Index: 1.4500 (estimate)
• Boiling Point: 424.9°Cat760mmHg
• Flash Point: 156.4°C
• PSA: 46.53000
• Density: 1.15g/cm³
• LogP: 3.50170
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 258.125594432
• Heavy Atom Count: 19
• Complexity: 324

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(CC1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O

Technology Process of 3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid

There total 1 articles about 3-(6-Methoxynaphthalen-2-yl)-2,2-dimethylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(6-methoxy-[2]naphthyl)-2,2-dimethyl-3-oxo-propionic acid ethyl ester (101743-90-2) → 3-(6-methoxy-[2]naphthyl)-2,2-dimethyl-propionic acid (63021-00-1)

Guidance literature:

With hydrogenchloride; amalgamated zinc; toluene; Behandeln des Reaktionsprodukts mit wss. Natronlauge und Dimethylsulfat;

DOI:10.1007/s004380000324

upstream raw materials:

3-(6-methoxy-[2]naphthyl)-2,2-dimethyl-3-oxo-propionic acid ethyl ester