1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-
CAS No.:131338-48-2
Molecular Formula:C23H13Br2N3O4
Molecular Weight:555.175
Hs Code.:
DSSTox Substance ID:DTXSID60157004
Wikidata:Q83025130

Synonyms:BRN 4771132;1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-;131338-48-2;1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-;C23H13Br2N3O4;DTXSID60157004;C23-H13-Br2-N3-O4;LS-84536

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Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-

Chemical Property:

Vapor Pressure:2.69E-22mmHg at 25°C
Boiling Point:734.4°Cat760mmHg
Flash Point:398°C
Density:1.84g/cm³
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:554.92523
Heavy Atom Count:32
Complexity:804

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CC3=NC4=C(C=C(C=C4Br)Br)C(=O)N3C5=CC=C(C=C5)O

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)-

There total 3 articles about 1H-Isoindole-1,3(2H)-dione, 2-((6,8-dibromo-3,4-dihydro-3-(4-hydroxy-3-(4-hydroxyphenyl)-4-oxo-2-quinazolinyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 123-30-8
4-amino-phenol

: 134716-08-8
2-(6,8-Dibromo-4-oxo-4H-benzo[d][1,3]oxazin-2-ylmethyl)-isoindole-1,3-dione

: 131338-48-2
2-[6,8-Dibromo-3-(4-hydroxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: With pyridine; Heating;

Reference yield:

: 6780-38-7
N-phthaloylglycine chloride

: 131338-48-2
2-[6,8-Dibromo-3-(4-hydroxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0 to 5 deg C, 1h, 2) RT, overnight

2: 75 percent / pyridine / Heating

With pyridine;

Reference yield:

: 609-85-8
2-amino-3,5-dibromobenzoic acid

: 131338-48-2
2-[6,8-Dibromo-3-(4-hydroxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1) 0 to 5 deg C, 1h, 2) RT, overnight

2: 75 percent / pyridine / Heating

With pyridine;