5-Fluoro-2-methylphenylhydrazine hydrochloride

Base Information

• Chemical Name: 5-Fluoro-2-methylphenylhydrazine hydrochloride
• CAS No.: 325-50-8
• Molecular Formula: C7H9 F N2 . Cl H
• Molecular Weight: 176.621
• Hs Code.: 2928000090
• Mol file: 325-50-8.mol

Synonyms:Hydrazine,(5-fluoro-2-methylphenyl)-, monohydrochloride (9CI); Hydrazine,(5-fluoro-o-tolyl)-, hydrochloride (8CI); (5-Fluoro-2-methylphenyl)hydrazinehydrochloride

Chemical Property of 5-Fluoro-2-methylphenylhydrazine hydrochloride

Chemical Property:

• Vapor Pressure: 0.177mmHg at 25°C
• Melting Point: 197°C (dec.)
• Boiling Point: 212 °C at 760 mmHg
• Flash Point: 82 °C
• PSA: 38.05000
• Density: 1.498g/cm³
• LogP: 2.99500
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

5-Fluoro-2-methylphenylhydrazinehydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 20/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Fluoro-2-methylphenylhydrazine, HCl

Technology Process of 5-Fluoro-2-methylphenylhydrazine hydrochloride

There total 1 articles about 5-Fluoro-2-methylphenylhydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

3-fluoro-6-methylaniline (367-29-3) → (5-fluoro-2-methylphenyl)hydrazine hydrochloride (325-50-8)

Guidance literature:

3-fluoro-6-methylaniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 1h;

With tin(ll) chloride; In water; at 20 ℃; for 2h;

Reference yield: 88.0%

2-oxo-propionic acid ethyl ester (617-35-6) + (5-fluoro-2-methylphenyl)hydrazine hydrochloride (325-50-8) → ethyl (2E)-2-[2-(5-fluoro-2-methylphenyl) hydrazin-1-ylidene]propanoate

Guidance literature:

With sulfuric acid; In ethanol; at 25 ℃; for 2h;

Reference yield: 75.9%

methyl 3-methoxyprop-2-enoate (34846-90-7) + (5-fluoro-2-methylphenyl)hydrazine hydrochloride (325-50-8) → 1-(5-fluoro-2-methylphenyl)-5-hydroxypyrazole

Guidance literature:

In methanol; for 6h; Reflux;

upstream raw materials:

3-fluoro-6-methylaniline

Refernces