Inosine, 6-S-(3-methylbutyl)-6-thio-, 2',3',5'-tris(4-methylbenzoate)

Base Information

Chemical Name:Inosine, 6-S-(3-methylbutyl)-6-thio-, 2',3',5'-tris(4-methylbenzoate)
CAS No.:849936-62-5
Molecular Formula:C39H40N4O7S
Molecular Weight:708.835
Hs Code.:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Inosine, 6-S-(3-methylbutyl)-6-thio-, 2',3',5'-tris(4-methylbenzoate)

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Technology Process of Inosine, 6-S-(3-methylbutyl)-6-thio-, 2',3',5'-tris(4-methylbenzoate)

There total 1 articles about Inosine, 6-S-(3-methylbutyl)-6-thio-, 2',3',5'-tris(4-methylbenzoate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 541-31-1
3-methylbutanethiol

: 756494-14-1
6-chloro-9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]purine

: 849936-62-5
9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-[(3-methylbutyl)sulfanyl]purine

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃;
DOI:10.1021/ol050063s

Reference yield: 71.0%

: 849936-62-5
9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-[(3-methylbutyl)sulfanyl]purine

: 1765-93-1
4-fluoroboronic acid

: 6-(4-fluorophenyl)-9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]purine

Guidance literature:: With 1,3-bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene hydrochloride; potassium carbonate; palladium diacetate; In toluene; at 90 ℃; for 8h;
DOI:10.1021/ol050063s

Reference yield: 69.0%

: 849936-62-5
9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-[(3-methylbutyl)sulfanyl]purine

: 5720-05-8
4-methylphenylboronic acid

: 9-[2,3,5-tri-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-(4-methylphenyl)purine

Guidance literature:: With 1,3-bis(2,6-diisopropylphenyl)imidazolidin-2-ylidene hydrochloride; potassium carbonate; palladium diacetate; In toluene; at 90 ℃; for 8h;
DOI:10.1021/ol050063s