2-Methyl-1,2-di-4-pyridinyl-1-propanone

Base Information

Chemical Name:2-Methyl-1,2-di-4-pyridinyl-1-propanone
CAS No.:17286-92-9
Molecular Formula:C₁₄H₁₄N₂O
Molecular Weight:226.278
Hs Code.:
DSSTox Substance ID:DTXSID10938224
Nikkaji Number:J395.254A
Wikidata:Q82914494
Mol file:17286-92-9.mol

Synonyms:2-methyl-1,2(bispyridyl)-1-propanone;metapyrone

Suppliers and Price of 2-Methyl-1,2-di-4-pyridinyl-1-propanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-1,2-di-4-pyridinyl-1-propanone
500mg
$ 105.00

Total 17 raw suppliers

Chemical Property of 2-Methyl-1,2-di-4-pyridinyl-1-propanone

Chemical Property:

Vapor Pressure:2.79E-06mmHg at 25°C
Boiling Point:389.7°Cat760mmHg
Flash Point:192.4°C
PSA：42.85000
Density:1.12g/cm³
LogP:2.63710
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:226.110613074
Heavy Atom Count:17
Complexity:263

Purity/Quality:

99% ^*data from raw suppliers

2-Methyl-1,2-di-4-pyridinyl-1-propanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C1=CC=NC=C1)C(=O)C2=CC=NC=C2
Uses 2-Methyl-1,2-di-4-pyridinyl-1-propanone is an analog of Metyrapone (M338990). Studies show that 2-Methyl-1,2-di-4-pyridinyl-1-propanone induced blockage of 18-hydroxylation in the adrenal cortex of rats which increased the activity in the zona glomerulosa and of the mineralocorticoids.

Technology Process of 2-Methyl-1,2-di-4-pyridinyl-1-propanone

There total 3 articles about 2-Methyl-1,2-di-4-pyridinyl-1-propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69267-29-4
<2,3-bis(4-pyridyl)-2,3-butanediol>

: 17286-92-9
1,2-Di-4-pyridyl-2-methyl-1-propanon

Guidance literature:: With sulfuric acid;
DOI:10.1021/ja01524a050

Reference yield:

: 1122-54-9
methyl (4-pyridyl) ketone

: 17286-92-9
1,2-Di-4-pyridyl-2-methyl-1-propanon

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol; acetic acid / Einwirkung von UV-Licht

2: concentrated H₂SO₄

With sulfuric acid; acetic acid; isopropyl alcohol;
DOI:10.1021/ja01524a050