Derric acid

Base Information

• Chemical Name: Derric acid
• CAS No.: 41743-39-9
• Molecular Formula: C12H14O7
• Molecular Weight: 270.239
• Mol file: 41743-39-9.mol

Synonyms:Derrsaeure;(2-carboxymethoxy-4,5-dimethoxy-phenyl)-acetic acid;(2-Carboxymethoxy-4,5-dimethoxy-phenyl)-essigsaeure;2--4,5-dimethoxy-phenylessigsaeure;4,5-Dimethoxy-2-carboxymethyl-phenoxyessigsaeure, Derricsaeure;2-Carboxymethoxy-4,5-dimethoxy-phenylessigsaeure;

Chemical Property of Derric acid

Chemical Property:

• Melting Point: 165 °C
• PSA: 102.29000
• LogP: 0.79430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Derric acid

There total 9 articles about Derric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-carboxymethoxy-4,5-dimethoxy-phenyl)-pyruvic acid (856095-60-8) → 4,5-dimethoxy-2-carboxymethoxyphenylacetic acid (41743-39-9)

Guidance literature:

With sodium hydroxide; dihydrogen peroxide;

DOI:10.1039/jr9320001380

Reference yield:

(2-ethoxycarbonylmethoxy-4,5-methoxyphenyl)hydroxyacetonitrile (76322-14-0) → 4,5-dimethoxy-2-carboxymethoxyphenylacetic acid (41743-39-9)

Guidance literature:

With hydrogenchloride; hydrogen iodide; acetic acid; tin(ll) chloride; for 3h; Heating;

DOI:10.1002/bscb.19800890607

Reference yield:

3,4-dimethoxyphenol (2033-89-8) → 4,5-dimethoxy-2-carboxymethoxyphenylacetic acid (41743-39-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) hydrogen chloride, potassium chloride 2.) water / 1.) ether, -5 deg C 2.) reflux, 1 h

2: 86 percent / potassium carbonate, potassium iodide / 4 h / Heating

3: 1.) potassium metabisulfite / 1.) 50 deg C, water 2.) water, ether, 5 deg C, 6 h

4: stannous chloride dihydrate, cc. hydrogen chloride, acetic acid, hydrogen iodide / 3 h / Heating

With hydrogenchloride; potassium disulphite; potassium chloride; water; hydrogen iodide; potassium carbonate; acetic acid; potassium iodide; tin(ll) chloride;

DOI:10.1002/bscb.19800890607

upstream raw materials:

(2-carboxymethoxy-4,5-dimethoxy-phenyl)-pyruvic acid

(2-ethoxycarbonylmethoxy-4,5-methoxyphenyl)hydroxyacetonitrile

4-(3'-hydroxy-4'-methoxyphenyl)-6-formyl-7-hydroxy-5-methoxy-2H-1-benzopyran-2-one, voludal

dimethyl sulfate

Downstream raw materials:

ethyl(2-ethoxycarbonylmethoxy-4,5-methoxyphenyl)acetate

2-carboxymethoxy-4,5-dimethoxy-benzoic acid

methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate