Ccris 4434

Base Information

• Chemical Name: Ccris 4434
• CAS No.: 116355-84-1
• Molecular Formula: C₃₄H₅₉NO₁₄
• Molecular Weight: 705.841
• Hs Code.: 29221990
• Wikipedia: Fumonisin_B2
• Wikidata: Q104199027
• Mol file: 116355-84-1.mol

Synonyms:fumonisin B2;fumonisin-B2

Chemical Property of Ccris 4434

Chemical Property:

• Vapor Pressure: 7.57E-35mmHg at 25°C
• Melting Point: <3200(dec)
• Refractive Index: 1.6630 (estimate)
• Boiling Point: 864.4 °C at 760 mmHg
• PKA: 3?+-.0.23(Predicted)
• Flash Point: 476.6 °C
• PSA: 268.28000
• Density: 1.222 g/cm³
• LogP: 4.29370
• Storage Temp.: −20°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 31
• Exact Mass: 705.39355556
• Heavy Atom Count: 49
• Complexity: 1040

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fumonisin B2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T+
• Hazard Codes: T+,T,Xn,F
• Statements: 26/27/28-36/37/38-40-36-20/21/22-11
• Safety Statements: 22-36/37/39-45-36/37-16-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
• Description: Fumonisin B2 belongs to the family of toxins known as fumonisins. It is produced by several species of Fusarium molds primarily by Fusarium verticillioide. It is one of the major mycotoxin contaminant in corn and corn-based foods. Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than the latter and it inhibits sphinganine-N-acetyltransferase (ceramide synthase).Fumonisin B2 is a carcinogenic mycotoxin generally present on corn based food and feed-stuff, which is produced by the fungus Fusarium verticillioides and Fusarium moniliforme. Fumonisin B2 can also be detected in the industrially important fungi, Aspergillus niger.
• Uses: A mycotoxin produced by mold associated with corn. Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine. Fumonisin B2 is a minor analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. To date much of the research on the pharmacology of the fumonisins has focused on fumonisin B1. It is generally accepted that fumonisin B2 acts on ceramide biosynthesis, however, the pharmacology of the minor analogues is less well explored. Contact herbicide used also to produce desiccation and defoliation

Technology Process of Ccris 4434

There total 1 articles about Ccris 4434 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(R)-3-Benzyloxycarbonyl-pentanedioic acid benzyl ester (Z)-(1R,2S,4S,11R,13S,14S)-11,13-bis-benzyloxy-2-((R)-3,4-bis-benzyloxycarbonyl-butyryloxy)-14-dibenzylamino-4-methyl-1-((R)-1-methyl-pentyl)-pentadec-6-enyl ester → fumonisin B2 (116355-84-1)

Guidance literature:

With hydrogenchloride; hydrogen; palladium dihydroxide; In tetrahydrofuran; tert-butyl alcohol; under 760 Torr; Ambient temperature;

DOI:10.1021/jo9711347

Refernces