2-Methyl-4,6-bis(N,N-dimethylaminophenyl)thiopyrliumiodide

Base Information

• Chemical Name: 2-Methyl-4,6-bis(N,N-dimethylaminophenyl)thiopyrliumiodide
• CAS No.: 151921-87-8
• Molecular Formula: C₂₂H₂₅N₂S*I
• Molecular Weight: 476.424
• Mol file: 151921-87-8.mol

Synonyms:Thiopyrylium,2,4-bis[4-(dimethylamino)phenyl]-6-methyl-, iodide (9CI)

Chemical Property of 2-Methyl-4,6-bis(N,N-dimethylaminophenyl)thiopyrliumiodide

Chemical Property:

• PSA: 31.55000
• LogP: 1.88380

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-4,6-bis(N,N-dimethylaminophenyl)thiopyrliumiodide

There total 2 articles about 2-Methyl-4,6-bis(N,N-dimethylaminophenyl)thiopyrliumiodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2-[4-(dimethylamino)phenyl]-6-methyl-4H-thiopyran-4-one + 4-bromo-N,N-dimethylaniline (586-77-6) → 2-methyl-4,6-bis-(4-N,N-dimethylaminophenyl) thiopyrylium iodide (151921-87-8)

Guidance literature:

4-bromo-N,N-dimethylaniline; With magnesium; In tetrahydrofuran; for 2h; Heating;

2-[4-(dimethylamino)phenyl]-6-methyl-4H-thiopyran-4-one; In tetrahydrofuran; for 1h; Heating;

With hydrogen iodide; In tetrahydrofuran; water; at 0 ℃; for 1h; Further stages.;

DOI:10.1016/j.bmc.2007.04.033

Reference yield:

→ 2-methyl-4,6-bis-(4-N,N-dimethylaminophenyl) thiopyrylium iodide (151921-87-8)

Guidance literature:

upstream raw materials:

4-bromo-N,N-dimethylaniline

Refernces

• 1、 -. "Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds". . . Retrieved 2008/06/13.