Technology Process of 9,10-Dihydro-2,6-dihydroxy-7,8-dimethoxy-5H-phenanthro[4,5-bcd]pyran-5-one
There total 27 articles about 9,10-Dihydro-2,6-dihydroxy-7,8-dimethoxy-5H-phenanthro[4,5-bcd]pyran-5-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethyl acetate;
for 72h;
under 15001.5 Torr;
DOI:10.1021/ja411146x
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 4.4 g / hydrogen chloride, zinc chloride / 1,2-dichloro-ethane / 1.) 40 deg C, 3.75 h, 2.) 15 h, RT
2: 1.85 g / toluene / 45 h / 60 °C
3: lithium methoxide / methanol; dimethylformamide
4: 1.034 g / methanol; dimethylformamide / 4.5 h / 90 °C
5: 157 mg / cyclohexane / 4.5 h / Irradiation
6: 214 mg / hydrogen / palladized charcoal / acetic acid / 96 h
7: 22.5 mg / boron trichloride / CH2Cl2 / 24 h / Ambient temperature
With
hydrogenchloride; lithium methanolate; hydrogen; boron trichloride; zinc(II) chloride;
palladium on activated charcoal;
In
methanol; dichloromethane; cyclohexane; acetic acid; 1,2-dichloro-ethane; N,N-dimethyl-formamide; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.85 g / toluene / 45 h / 60 °C
2: lithium methoxide / methanol; dimethylformamide
3: 1.034 g / methanol; dimethylformamide / 4.5 h / 90 °C
4: 157 mg / cyclohexane / 4.5 h / Irradiation
5: 214 mg / hydrogen / palladized charcoal / acetic acid / 96 h
6: 22.5 mg / boron trichloride / CH2Cl2 / 24 h / Ambient temperature
With
lithium methanolate; hydrogen; boron trichloride;
palladium on activated charcoal;
In
methanol; dichloromethane; cyclohexane; acetic acid; N,N-dimethyl-formamide; toluene;