5-Pyrimidinepropanoicacid, 2-amino-1,6-dihydro-4-methyl-6-oxo-

Base Information

• Chemical Name: 5-Pyrimidinepropanoicacid, 2-amino-1,6-dihydro-4-methyl-6-oxo-
• CAS No.: 90091-19-3
• Molecular Formula: C8H11 N3 O3
• Molecular Weight: 197.194
• Mol file: 90091-19-3.mol

Synonyms:5-Pyrimidinepropanoicacid, 2-amino-1,4-dihydro-6-methyl-4-oxo- (9CI); 5-Pyrimidinepropionic acid,2-amino-4-hydroxy-6-methyl- (7CI); NSC 79670

Chemical Property of 5-Pyrimidinepropanoicacid, 2-amino-1,6-dihydro-4-methyl-6-oxo-

Chemical Property:

• Vapor Pressure: 3.21E-08mmHg at 25°C
• Boiling Point: 419.7°Cat760mmHg
• Flash Point: 207.6°C
• PSA: 109.07000
• Density: 1.51g/cm³
• LogP: 0.25890

Purity/Quality:

3-(2-amino-6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)propanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Pyrimidinepropanoicacid, 2-amino-1,6-dihydro-4-methyl-6-oxo-

There total 2 articles about 5-Pyrimidinepropanoicacid, 2-amino-1,6-dihydro-4-methyl-6-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propionic acid ethyl ester; hydrochloride → 3-(2-amino-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)propanoic acid (90091-19-3)

Guidance literature:

With sodium hydroxide; water;

Reference yield:

→ 3-(2-amino-4-methyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-propionic acid (90091-19-3)

Guidance literature:

2-Amino-4-hydroxy-6-methyl-5-pyrimidin-propionitril (6n HCl, Sdet., 2h);

DOI:10.1021/jm00331a007

Reference yield: 8.6%

3-(2-amino-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)propanoic acid (90091-19-3) + N-methylaniline (100-61-8) → 3-(2-amino-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)-N-methyl-N-phenylpropanamide

Guidance literature:

3-(2-amino-4-methyl-6-oxo-1,6-dihydropyrimidin-5-yl)propanoic acid; With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

N-methylaniline; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;