[2-(3,4-dichlorophenyl)-5-methylfuran-3,4-diyl]dimethanediyl bis(methylcarbamate)

Base Information

• Chemical Name: [2-(3,4-dichlorophenyl)-5-methylfuran-3,4-diyl]dimethanediyl bis(methylcarbamate)
• CAS No.: 92126-09-5
• Molecular Formula: C17H18 Cl2 N2 O5
• Molecular Weight: 401.2412
• Mol file: 92126-09-5.mol

Synonyms:NSC 301489

Chemical Property of [2-(3,4-dichlorophenyl)-5-methylfuran-3,4-diyl]dimethanediyl bis(methylcarbamate)

Chemical Property:

• Vapor Pressure: 4.16E-12mmHg at 25°C
• Boiling Point: 549.1°Cat760mmHg
• Flash Point: 285.9°C
• Density: 1.333g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [2-(3,4-dichlorophenyl)-5-methylfuran-3,4-diyl]dimethanediyl bis(methylcarbamate)

There total 3 articles about [2-(3,4-dichlorophenyl)-5-methylfuran-3,4-diyl]dimethanediyl bis(methylcarbamate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

methyl isocyanate (624-83-9) + [2-(3,4-Dichloro-phenyl)-4-hydroxymethyl-5-methyl-furan-3-yl]-methanol (92126-13-1) → 2-methyl-3,4-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)furan bis(methylcarbamate) (92126-09-5)

Guidance literature:

With triethylamine; In chloroform; for 17.5h; Heating;

DOI:10.1021/jm00378a006

Reference yield:

2-(3,4-Dichloro-phenyl)-5-methyl-furan-3,4-dicarboxylic acid dimethyl ester (92126-12-0) → 2-methyl-3,4-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)furan bis(methylcarbamate) (92126-09-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / LiAlH₄ / diethyl ether / 1.5 h / Heating

2: 74 percent / Et₃N / CHCl₃ / 17.5 h / Heating

With lithium aluminium tetrahydride; triethylamine; In diethyl ether; chloroform;

DOI:10.1021/jm00378a006

Reference yield:

<1-(dimethylsulfonio)ethyl 3,4-dichlorophenyl ketone> bromide (92126-10-8) → 2-methyl-3,4-bis(hydroxymethyl)-5-(3,4-dichlorophenyl)furan bis(methylcarbamate) (92126-09-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) K₂CO₃, NaOH / 2.) DMSO, 4 h

2: 95 percent / LiAlH₄ / diethyl ether / 1.5 h / Heating

3: 74 percent / Et₃N / CHCl₃ / 17.5 h / Heating

With sodium hydroxide; lithium aluminium tetrahydride; potassium carbonate; triethylamine; In diethyl ether; chloroform;

DOI:10.1021/jm00378a006

upstream raw materials:

methyl isocyanate

[2-(3,4-Dichloro-phenyl)-4-hydroxymethyl-5-methyl-furan-3-yl]-methanol

2-(3,4-Dichloro-phenyl)-5-methyl-furan-3,4-dicarboxylic acid dimethyl ester

<1-(dimethylsulfonio)ethyl 3,4-dichlorophenyl ketone> bromide