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Technology Process of 2-(Chloromethyl)oxirane; prop-2-en-1-amine

2-(Chloromethyl)oxirane; prop-2-en-1-amine

Base Information
  • Chemical Name:2-(Chloromethyl)oxirane; prop-2-en-1-amine
  • CAS No.:52757-95-6
  • Molecular Formula:C6H12ClNO
  • Molecular Weight:149.61858
  • Hs Code.:
  • Wikipedia:Sevelamer
  • NCI Thesaurus Code:C84172
  • RXCUI:214824
  • Metabolomics Workbench ID:145396
  • ChEMBL ID:CHEMBL1201798
  • Mol file:52757-95-6.mol
2-(Chloromethyl)oxirane; prop-2-en-1-amine

Synonyms:Carbonate, Sevelamer;GT335 012;GT335-012;GT335012;Hydrochloride, Sevelamer;RenaGel;sevelamer;sevelamer carbonate;sevelamer hydrochloride

Suppliers and Price of 2-(Chloromethyl)oxirane; prop-2-en-1-amine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • DC Chemicals
  • Sevelamer >98%
  • 1 g
  • $ 400.00
  • DC Chemicals
  • Sevelamer >98%
  • 100 mg
  • $ 100.00
Total 35 raw suppliers
Chemical Property of 2-(Chloromethyl)oxirane; prop-2-en-1-amine
Chemical Property:
  • Boiling Point:116.1°Cat760mmHg 
  • Flash Point:33.9°C 
  • PSA：38.55000 
  • Density:g/cm3 
  • LogP:1.45540 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:2
  • Exact Mass:149.0607417
  • Heavy Atom Count:9
  • Complexity:55.1
Purity/Quality:

99%, *data from raw suppliers

Sevelamer >98% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C=CCN.C1C(O1)CCl
  • Recent ClinicalTrials:Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)
  • Recent EU Clinical Trials:An open-label, randomized, active controlled multi center phase II dose finding study to evaluate the ability of PA21 to lower serum phosphate levels and the tolerability in patients with chronic kidney disease on maintenance hemodialysis
  • Recent NIPH Clinical Trials:Efficacy and tolerability of bixalomer for treatment of hyperphosphatemia in maintenance hemodialysis patients with poor tolerance to sevelamer: a switching study.
  • Clinical Use Phosphate-binding agent
  • Drug interactions Potentially hazardous interactions with other drugs Antibacterials: reduces bioavailability of ciprofloxacin. Ciclosporin: possibly reduces ciclosporin concentration. Calcitriol: absorption may be impaired by sevelamer. Mycophenolate: may reduce mycophenolate levels. Tacrolimus: possibly reduces tacrolimus concentration. Thyroid hormones: possibly reduces levothyroxine concentration.
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