4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide

Base Information

Chemical Name:4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide
CAS No.:851083-43-7
Molecular Formula:C18H15N3O2
Molecular Weight:305.336
Hs Code.:
DSSTox Substance ID:DTXSID50463146
Wikidata:Q82287946

Synonyms:851083-43-7;4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide;DTXSID50463146

Suppliers and Price of 4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:305.116426730
Heavy Atom Count:23
Complexity:442

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=C(C(=N1)C(=O)N)C(=O)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide

There total 3 articles about 4-Benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 851083-42-6
4-benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carbonyl chloride

: 851083-43-7
4-benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid amide

Guidance literature:: With ammonia; In tetrachloromethane; for 0.5h;
DOI:10.1016/j.ejmech.2004.12.001

Reference yield:

: 851083-40-4
4-benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid

: 851083-43-7
4-benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / SOCl₂ / 5 h / Heating

2: 65 percent / ammonia / CCl₄ / 0.5 h / cooling

With thionyl chloride; ammonia; In tetrachloromethane;
DOI:10.1016/j.farmac.2004.09.003

Reference yield:

: 17571-17-4
4-benzoyl-5-phenyl-furan-2,3-dione

: 851083-43-7
4-benzoyl-1-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1: 45 percent / benzene / 1 h / 20 °C

2: 68 percent / SOCl₂ / 5 h / Heating

3: 65 percent / ammonia / CCl₄ / 0.5 h / cooling

With thionyl chloride; ammonia; In tetrachloromethane; benzene;
DOI:10.1016/j.farmac.2004.09.003