5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil

Base Information

Chemical Name:5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil
CAS No.:132774-45-9
Molecular Formula:C15H18 N2 O3 S
Molecular Weight:306.386
Hs Code.:
Mol file:132774-45-9.mol

Synonyms:E-EPU

Suppliers and Price of 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil

Chemical Property:

Melting Point:123-125 °C
Boiling Point:°Cat760mmHg
PKA:8.59±0.40(Predicted)
Flash Point:°C
PSA：89.65000
Density:1.27g/cm³
LogP:2.65650

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil

There total 3 articles about 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 136011-43-3
5-ethyl-1-ethoxymethyl-6-(phenylthio)-2-thiouracil

: 132774-45-9
5-ethyl-1-(ethoxymethyl)-6-(phenylthio)uracil

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; for 1h; Ambient temperature;
DOI:10.1021/jm00103a009

Reference yield:

: 34171-37-4
5-ethyl-2-thiouracil

: 132774-45-9
5-ethyl-1-(ethoxymethyl)-6-(phenylthio)uracil

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) (NH₄)2SO₄, 1,1,1,3,3,3-hexamethyldisilazane, 2.) CsI / 1.) reflux, 15 h, 2.) MeCN, reflux, 2 h

2: 1.) lithium diisopropylamide (LDA) / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

3: 77 percent / 1 N aq. NaOH, 35percent H₂O₂ / 1 h / Ambient temperature

With ammonium sulfate; sodium hydroxide; isocyanate de chlorosulfonyle; dihydrogen peroxide; 1,1,1,3,3,3-hexamethyl-disilazane; lithium diisopropyl amide;
DOI:10.1021/jm00103a009

Reference yield:

: 144410-13-9
1-(ethoxymethyl)-5-ethyl-2-thiouracil

: 132774-45-9
5-ethyl-1-(ethoxymethyl)-6-(phenylthio)uracil

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) lithium diisopropylamide (LDA) / 1.) THF, -70 deg C, 1 h, 2.) THF, -70 deg C, 1 h

2: 77 percent / 1 N aq. NaOH, 35percent H₂O₂ / 1 h / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; lithium diisopropyl amide;
DOI:10.1021/jm00103a009