1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline

Base Information

Chemical Name:1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline
CAS No.:96719-46-9
Molecular Formula:C₂₂H₂₁NO
Molecular Weight:315.415
Hs Code.:
DSSTox Substance ID:DTXSID80914378
Nikkaji Number:J1.691.141K

Synonyms:1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline;96719-46-9;Isoquinoline, 1,2,3,4-tetrahydro-1,2-diphenyl-6-methoxy-;SCHEMBL6715323;6-methoxy-1,2-diphenyl-1,2,3,4-tetrahydroisoquinoline;DTXSID80914378;1,2-DIPHENYL-6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE;LS-85964

Suppliers and Price of 1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline

Chemical Property:

Vapor Pressure:2.23E-09mmHg at 25°C
Boiling Point:480.1°Cat760mmHg
Flash Point:139.5°C
Density:1.127g/cm³
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:315.162314293
Heavy Atom Count:24
Complexity:385

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(N(CC2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline

There total 9 articles about 1,2,3,4-Tetrahydro-1,2-diphenyl-6-methoxyisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96718-82-0
N-[2-(3-methoxy-phenyl)-ethyl]-N-phenyl-benzamide

: 96719-46-9
6-methoxy-1,2-diphenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: N-[2-(3-methoxy-phenyl)-ethyl]-N-phenyl-benzamide; With trichlorophosphate; Heating;

With sodium tetrahydroborate; In methanol;
DOI:10.1016/j.bmcl.2004.03.077

Reference yield:

: 51009-27-9
[2-(3-Methoxy-phenyl)-ethyl]-phenyl-amine

: 96719-46-9
6-methoxy-1,2-diphenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-propanephosphonic cyclic anhydride; DMAP; Et₃N / CH₂Cl₂

2.1: POCl₃ / Heating

2.2: NaBH₄ / methanol

With dmap; triethylamine; 1-propanephosphonic acid cyclic anhydride; trichlorophosphate; In dichloromethane; 2.1: Bischler-Napieralski cyclization;
DOI:10.1016/j.bmcl.2004.03.077

Reference yield:

: 65-85-0,8013-63-6
benzoic acid

: 96719-46-9
6-methoxy-1,2-diphenyl-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-propanephosphonic cyclic anhydride; DMAP; Et₃N / CH₂Cl₂

2.1: POCl₃ / Heating

2.2: NaBH₄ / methanol

With dmap; triethylamine; 1-propanephosphonic acid cyclic anhydride; trichlorophosphate; In dichloromethane; 2.1: Bischler-Napieralski cyclization;
DOI:10.1016/j.bmcl.2004.03.077