2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one

Base Information

Chemical Name:2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one
CAS No.:851728-60-4
Molecular Formula:C₂₁H₁₇Cl₂F₂N₃O₂
Molecular Weight:452.288
Hs Code.:
UNII:45FRJ4YGM2
ChEMBL ID:CHEMBL484929
DSSTox Substance ID:DTXSID80462142
Wikidata:Q7119052
Wikipedia:PF-514273
Mol file:851728-60-4.mol

Synonyms:2-(2-chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo(3,4-f)(1,4)oxazepin-8(5H)-one;PF 514273;PF-514273;PF514273

Suppliers and Price of 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
PF-514273
10mg
$ 425.00

Usbiological
PF-514273
5mg
$ 425.00

Usbiological
PF 514273
10mg
$ 480.00

Tocris
PF514273 ≥98%(HPLC)
50
$ 906.00

Tocris
PF514273 ≥98%(HPLC)
10
$ 222.00

Sigma-Aldrich
PF-514273 ≥98% (HPLC)
25mg
$ 439.00

Sigma-Aldrich
PF-514273 ≥98% (HPLC)
5mg
$ 109.00

Medical Isotopes, Inc.
PF-514273
1 g
$ 8500.00

ApexBio Technology
PF514273
50mg
$ 1385.00

ApexBio Technology
PF514273
10mg
$ 339.00

Total 11 raw suppliers

Chemical Property of 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one

Chemical Property:

Melting Point:158-160°C
PSA：47.36000
LogP:5.27380
Storage Temp.:Store at +4°C
Solubility.:DMSO: >5mg/mL (warmed)
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:451.0665885
Heavy Atom Count:30
Complexity:621

Purity/Quality:

97% ^*data from raw suppliers

PF-514273 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CN1CCOC2=C(N(N=C2C1=O)C3=CC=CC=C3Cl)C4=CC=C(C=C4)Cl)(F)F
Uses A novel, bicyclic lactam-based cannabinoid-1 receptor antagonist for the treatment of obesity.

Technology Process of 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one

There total 2 articles about 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-F][1,4]oxazepin-8(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%