B-HT 933 DIHYDROCHLORIDE

Base Information

• Chemical Name: B-HT 933 DIHYDROCHLORIDE
• CAS No.: 36067-72-8
• Molecular Formula: C9H15 N3 O . 2 Cl H
• Molecular Weight: 254.15678
• Mol file: 36067-72-8.mol

Synonyms:4H-Oxazolo[4,5-d]azepin-2-amine,6-ethyl-5,6,7,8-tetrahydro-, dihydrochloride (9CI); B-HT 933

Chemical Property of B-HT 933 DIHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.000162mmHg at 25°C
• Boiling Point: 330.9°Cat760mmHg
• Flash Point: 153.9°C
• PSA: 55.29000
• Density: 1.126g/cm³
• LogP: 2.80040
• Storage Temp.: Desiccate at RT
• Solubility.: H2O: >20 mg/mL

Purity/Quality:

99% ^*data from raw suppliers

B-HT933Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: B-HT 933 is an agonist of α2-adrenergic receptors (α2-ARs) with an EC50 value of 0.65 μM for contraction of canine sapheneous veins. It induces concentration-dependent inhibition of the twitch response in rat vas deferens and guinea pig ileum. B-HT 933 induces sedation and reduces motor activity in mice, an effect that is reversed by the α2-AR antagonist yohimbine . B-HT 933 decreases blood pressure and cardiac output in cats injected with 30 μg/kg intracisternally. It also exhibits antinociceptive effects in mice with ED50 values of 12.5, 20.5, and 6.1 mg/kg for the tail-immersion, tail-pinch, and acetic acid writhing tests, respectively.
• Uses: B-HT 933 Dihydrochloride is a selective α2-adrenoceptor agonist and has less potent inhibitory effect on the sympathetic vasopressor responses in diabetic rats.