Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-

Base Information

Chemical Name:Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-
CAS No.:85723-93-9
Molecular Formula:C12H12BrN3O
Molecular Weight:294.151
Hs Code.:
DSSTox Substance ID:DTXSID10384787
Wikidata:Q82177144

Synonyms:85723-93-9;Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-;Oprea1_313255;SCHEMBL11198966;DTXSID10384787;CCG-43295;SR-01000633224-1

Suppliers and Price of Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:293.01637
Heavy Atom Count:17
Complexity:281

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=C1Br)NC(=O)C2=CC=CC=C2)C

Technology Process of Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-

There total 1 articles about Benzamide, N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 54384-73-5
N-(1,3-Dimethyl-1H-pyrazol-5-yl)benzamide

: 85723-93-9
N-(4-Bromo-1,3-dimethyl-1H-pyrazol-5-yl)benzamide

Guidance literature:: With bromine; In acetic acid;

Reference yield: 62.0%

: 85723-93-9
N-(4-Bromo-1,3-dimethyl-1H-pyrazol-5-yl)benzamide

: 106-94-5
propyl bromide

: 103094-23-1
N-(4-bromo-1,3-dimethyl-1H-pyrazol-5-yl)-N-propylbenzamide

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 50 ℃; for 3h;
DOI:10.1021/jm00159a011

Reference yield:

: 85723-93-9
N-(4-Bromo-1,3-dimethyl-1H-pyrazol-5-yl)benzamide

: 103068-60-6
[1,3-dimethyl-5-(propylamino)-1H-pyrazol-4-yl](2-fluorophenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / NaH / dimethylformamide / 3 h / 50 °C

2: 1.) n-BuLi / 1.) THF, heptane, -60 deg C, 1.5 h, 2.) THF, from -60 deg C to 0 deg C

3: 45 percent / aq. H₂SO₄ / 5 h / 80 - 90 °C

With n-butyllithium; sulfuric acid; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00159a011