4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione

Base Information

Chemical Name:4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione
CAS No.:77165-71-0
Molecular Formula:C₂₀H₂₀N₂O₃
Molecular Weight:336.39
Hs Code.:
NSC Number:377126
Nikkaji Number:J562.592K

Synonyms:DA 3505;DA 3505, (E)-isomer;DA 3505, (Z)-isomer;DA-3505

Suppliers and Price of 4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione

Chemical Property:

Vapor Pressure:2.38E-10mmHg at 25°C
Boiling Point:488.3°Cat760mmHg
Flash Point:249.1°C
Density:1.244g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:336.14739250
Heavy Atom Count:25
Complexity:483

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)CO
Isomeric SMILES:C/C(=C\CC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)/CO

Technology Process of 4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione

There total 13 articles about 4-(4-Hydroxy-3-methylbut-2-en-1-yl)-1,2-diphenylpyrazolidine-3,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 73773-97-4
(Z)-4-(3-carbethoxy-but-2-enyl)-1,2-diphenyl-3,5-pyrazolidinedione

: 72487-09-3,77165-71-0
(Z)-4-(3-hydroxymethyl-but-2-enyl)-1,2-diphenyl-3,5-pyrazolidinedione

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In benzene; for 3h; Ambient temperature;

Reference yield: 43.0%

: 73773-96-3
(E)-4-(3-acetoxy-but-2-enyl)-1,2-diphenyl-3,5-pyrazolidinedione

: 77165-71-0
E-1,2-diphenyl-3,5-dioxo-4-(3'-hydroxymethyl-but-2'-enyl)pyrazolidine

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In benzene; for 3h; Ambient temperature;

Reference yield:

: 83113-49-9
(Z)-1-acetoxy-2-methyl-4-(N,N-di-n-butylamino)-but-2-ene

: 72487-09-3,77165-71-0
(Z)-4-(3-hydroxymethyl-but-2-enyl)-1,2-diphenyl-3,5-pyrazolidinedione

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / ClCOOEt / benzene / 2 h / Heating

2: 1) NaOEt / 1) DMF, H₂O, 0 deg C, 1 h then RT, 16 h

3: 5percent NaOH / 3 h / Ambient temperature

With sodium hydroxide; sodium ethanolate; chloroformic acid ethyl ester; In benzene;