(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine

Base Information

Chemical Name:(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
CAS No.:862270-48-2
Molecular Formula:C12H17FN2
Molecular Weight:208.279
Hs Code.:
DSSTox Substance ID:DTXSID60587802
Nikkaji Number:J2.593.649C
Mol file:862270-48-2.mol

Synonyms:(R)-1-(1-(4-FLUOROPHENYL)ETHYL)PIPERAZINE;862270-48-2;1-[(1R)-1-(4-fluorophenyl)ethyl]piperazine;(R)-1-[1-(4-fluorophenyl)ethyl]piperazine;(R)-1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE;SCHEMBL2264525;DTXSID60587802;PEOPJIYWTHRKKU-SNVBAGLBSA-N;MFCD11501368;AKOS022172757;DB-344843;CS-0170845

Suppliers and Price of (R)-1-(1-(4-Fluorophenyl)ethyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
50mg
$ 200.00

TRC
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
10mg
$ 45.00

Crysdot
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine 95+%
1g
$ 398.00

Chemenu
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine 95%
1g
$ 376.00

American Custom Chemicals Corporation
(R)-1-[1-(4-FLUORO-PHENYL)-ETHYL]-PIPERAZINE 95.00%
1G
$ 931.39

Alichem
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
250mg
$ 236.34

Alichem
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
1g
$ 573.30

AK Scientific
(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine
1g
$ 864.00

Total 11 raw suppliers

Chemical Property of (R)-1-(1-(4-Fluorophenyl)ethyl)piperazine

Chemical Property:

PSA：15.27000
LogP:2.05860
Storage Temp.:2-8°C(protect from light)
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:208.13757671
Heavy Atom Count:15
Complexity:184

Purity/Quality:

97% ^*data from raw suppliers

(R)-1-(1-(4-Fluorophenyl)ethyl)piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)F)N2CCNCC2
Isomeric SMILES:C[C@H](C1=CC=C(C=C1)F)N2CCNCC2

Technology Process of (R)-1-(1-(4-Fluorophenyl)ethyl)piperazine

There total 3 articles about (R)-1-(1-(4-Fluorophenyl)ethyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 862270-47-1
1-[(R)-1-(4-fluorophenyl)ethyl]-4-(toluene-4-sulfonyl)piperazine

: 862270-48-2
(R)-4-[1-(4-fluorophenyl)ethyl]piperazine

Guidance literature:: With hydrogen bromide; 4-hydroxy-benzoic acid; In acetic acid; at 20 ℃; for 48h;
DOI:10.1021/jm070191h

Reference yield:

: 374898-01-8
(R)-1-(4-fluorophenyl)ethylamine

: 862270-48-2
(R)-4-[1-(4-fluorophenyl)ethyl]piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / N,N-diisopropylethylamine / 20 h / 125 °C

2: 91 percent / 4-hydroxybenzoic acid; HBr / acetic acid / 48 h / 20 °C

With hydrogen bromide; N-ethyl-N,N-diisopropylamine; 4-hydroxy-benzoic acid; In acetic acid;
DOI:10.1021/jm070191h