Technology Process of 2-Furancarbonyl chloride, tetrahydro-2-methyl-5-oxo-, (S)- (9CI)
There total 1 articles about 2-Furancarbonyl chloride, tetrahydro-2-methyl-5-oxo-, (S)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
thionyl chloride;
In
benzene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 78 percent / LDA / diethyl ether / 2 h / -78 °C
2: 72 percent / aq. NaOH / Ambient temperature
3: 43 percent / NaH / THF, HMPA, 0 deg C, 1h; THF, HMPA, room temp., 5 h
4: 1.) LDA, 2.) 1 N aq. HCl / 1.) THF, -78 deg C, 1 h; room temp., 2 h
5: 61 percent / toluene / 1 h / Heating
6: 83 percent / 5percent aq. HCl / methanol / 48 h / Ambient temperature
With
hydrogenchloride; sodium hydroxide; sodium hydride; lithium diisopropyl amide;
In
methanol; diethyl ether; toluene;
