1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide

Base Information

Chemical Name:1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide
CAS No.:88598-54-3
Molecular Formula:C₂₀H₁₃NO₅
Molecular Weight:347.327
Hs Code.:
Mol file:88598-54-3.mol

Synonyms:trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydro-1-nitrobenzo[a]pyrene

Suppliers and Price of 1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide

Chemical Property:

Vapor Pressure:3.15E-18mmHg at 25°C
Boiling Point:658.3°C at 760 mmHg
Flash Point:351.9°C
PSA：98.81000
Density:1.699g/cm³
LogP:3.86320

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide

There total 9 articles about 1-nitrobenzo(a)pyrene-7,8-diol-9,10-epoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 88598-59-8
trans-7,8-Dihydroxy-7,8-dihydro-1-nitrobenzo pyrene

: 151592-32-4,88598-54-3
trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydro-1-nitrobenzo[a]pyrene

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; for 3h;
DOI:10.1021/jo00077a063

Reference yield:

: 132929-89-6
9,10-Dihydro-1-nitrobenzo pyrene

: 151592-32-4,88598-54-3
trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydro-1-nitrobenzo[a]pyrene

Guidance literature:: Multi-step reaction with 6 steps

1: 59 percent / I₂ / benzene / 18 h / Heating

2: 90 percent / NaOCH₃ / tetrahydrofuran; methanol / 0.5 h / 65 °C

3: 91 percent / pyridine / Ambient temperature

4: DDQ / dioxane / 54 h / Heating

5: 92 percent / NaOCH₃ / tetrahydrofuran; methanol / 0.5 h / 65 °C

6: 80 percent / m-chloroperbenzoic acid / tetrahydrofuran / 3 h

With pyridine; iodine; sodium methylate; 3-chloro-benzenecarboperoxoic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; 1,4-dioxane; methanol; benzene;
DOI:10.1021/jo00077a063

Reference yield:

: 120014-85-9
7-Hydroxy-7,8,9,10-tetrahydro-1-nitrobenzo pyrene

: 151592-32-4,88598-54-3
trans-7,8-Dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydro-1-nitrobenzo[a]pyrene

Guidance literature:: Multi-step reaction with 7 steps

1: 98 percent / p-toluenesulfonic acid / benzene / 1.67 h / Heating

2: 59 percent / I₂ / benzene / 18 h / Heating

3: 90 percent / NaOCH₃ / tetrahydrofuran; methanol / 0.5 h / 65 °C

4: 91 percent / pyridine / Ambient temperature

5: DDQ / dioxane / 54 h / Heating

6: 92 percent / NaOCH₃ / tetrahydrofuran; methanol / 0.5 h / 65 °C

7: 80 percent / m-chloroperbenzoic acid / tetrahydrofuran / 3 h

With pyridine; iodine; sodium methylate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; 1,4-dioxane; methanol; benzene;
DOI:10.1021/jo00077a063