1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

Base Information

Chemical Name:1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride
CAS No.:87049-35-2
Molecular Formula:C20H38Cl2N2O5
Molecular Weight:457.4321
Hs Code.:
DSSTox Substance ID:DTXSID801007302
Mol file:87049-35-2.mol

Synonyms:87049-35-2;1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride;2,6-Bis(2-hydroxy-3-((1-methylethyl)amino)propoxy)-alpha-methylbenzenemethanol 2HCl;Benzenemethanol, 2,6-bis(2-hydroxy-3-((1-methylethyl)amino)propoxy)-alpha-methyl-, dihydrochloride;DTXSID801007302;1-[2-(1-hydroxyethyl)-3-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol dihydrochloride;LS-30637;1,1'-{[2-(1-Hydroxyethyl)-1,3-phenylene]bis(oxy)}bis{3-[(propan-2-yl)amino]propan-2-ol}--hydrogen chloride (1/2)

Suppliers and Price of 1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

Chemical Property:

Boiling Point:558.2°Cat760mmHg
Flash Point:291.4°C
PSA：103.21000
Density:g/cm³
LogP:3.60110
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:13
Exact Mass:456.2157777
Heavy Atom Count:29
Complexity:353

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NCC(COC1=C(C(=CC=C1)OCC(CNC(C)C)O)C(C)O)O.Cl.Cl

Technology Process of 1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

There total 2 articles about 1-(alpha-Hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 87049-11-4
2,6-bis(2-hydroxy-3-isopropylaminopropoxy)acetophenone

: 87049-35-2
1-(α-hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

Guidance literature:: With potassium borohydride; In methanol; for 4h; Ambient temperature;

Reference yield:

: 699-83-2
2,6-dihydroxylacetophenone

: 87049-35-2
1-(α-hydroxyethyl)-2,6-bis(2-hydroxy-3-isopropylaminopropoxy)benzene dihydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / K₂CO₃ / 24 h / Heating

2: 70 percent / ethanol / 4 h / Heating

3: 92 percent / KBH₄ / methanol / 4 h / Ambient temperature

With potassium borohydride; potassium carbonate; In methanol; ethanol;