4-Ethynyl-3,6-dimethylpyridazine

Base Information

Chemical Name:4-Ethynyl-3,6-dimethylpyridazine
CAS No.:86520-98-1
Molecular Formula:C₈H₈N₂
Molecular Weight:132.165
Hs Code.:
DSSTox Substance ID:DTXSID501302424
Mol file:86520-98-1.mol

Synonyms:4-Ethynyl-3,6-dimethylpyridazine;86520-98-1;DTXSID501302424

Suppliers and Price of 4-Ethynyl-3,6-dimethylpyridazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Ethynyl-3,6-dimethylpyridazine

Chemical Property:

Melting Point:82-84 °C
Boiling Point:285.3±40.0 °C(Predicted)
PKA:2.39±0.10(Predicted)
PSA：25.78000
Density:1.05±0.1 g/cm3(Predicted)
LogP:1.07470
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:132.068748264
Heavy Atom Count:10
Complexity:156

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(N=N1)C)C#C

Technology Process of 4-Ethynyl-3,6-dimethylpyridazine

There total 2 articles about 4-Ethynyl-3,6-dimethylpyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 86521-13-3
3,6-Dimethyl-4-trimethylsilanylethynyl-pyridazine

: 86520-98-1
4-Ethynyl-3,6-dimethyl-pyridazine

Guidance literature:: With potassium hydroxide; In methanol; for 1h; Ambient temperature;
DOI:10.1055/s-1983-30319

Reference yield:

: 68206-05-3
4-chloro-3,6-dimethylpyridazine

: 86520-98-1
4-Ethynyl-3,6-dimethyl-pyridazine

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / bispalladium dichloride, copper(I) iodide, triethylamine / 12 h / 100 °C

2: 84 percent / aq. KOH / methanol / 1 h / Ambient temperature

With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; triethylamine; In methanol;
DOI:10.1055/s-1983-30319