4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile

Base Information

Chemical Name:4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile
CAS No.:865756-52-1
Molecular Formula:C15H11Br2NO2
Molecular Weight:397.066
Hs Code.:
DSSTox Substance ID:DTXSID80655815
Wikidata:Q82570110

Synonyms:4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile;865756-52-1;DTXSID80655815

Suppliers and Price of 4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:396.91360
Heavy Atom Count:20
Complexity:326

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Br)OCCOC2=CC=C(C=C2)C#N)Br

Technology Process of 4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile

There total 2 articles about 4-[2-(2,6-Dibromophenoxy)ethoxy]benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 865756-51-0
1,3-dibromo-2-[2-(p-toluenesulfonyloxy)ethoxy]benzene

: 767-00-0
4-cyanophenol

: 865756-52-1
1,3-dibromo-2-[4-(p-cyanophenyl)-1,4-dioxabutyl]benzene

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 24h;
DOI:10.1021/ja054069o

Reference yield:

: 608-33-3
2,6-dibromophenol

: 865756-52-1
1,3-dibromo-2-[4-(p-cyanophenyl)-1,4-dioxabutyl]benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / potassium carbonate / acetone / 24 h / 55 °C

2: 87 percent / potassium carbonate / dimethylformamide / 24 h / 100 °C

With potassium carbonate; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja054069o

Reference yield: 92.0%

: 865756-52-1
1,3-dibromo-2-[4-(p-cyanophenyl)-1,4-dioxabutyl]benzene

: 4-ethynylpyridine hydrochloride

: 865756-46-3
2-[4-(p-cyanophenyl)-1,4-dioxabutyl]-1,3-bis(4-pyridylethynyl)benzene

Guidance literature:: With bis(benzonitrile)palladium(II) dichloride; tri-tert-butyl phosphine; diisopropylamine; copper(l) iodide; In 1,4-dioxane; at 100 ℃; for 40h;
DOI:10.1021/ja054069o